5-[2-(3-Hydroxy-5-methoxyphenyl)ethyl]-2-methoxyphenol

Basic Information

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CAS Number

67884-30-4

Molecular Formula

C16H18O4

Molecular Weight

274.32 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Physical Properties

Physical State

Powder

Density

1.204±0.06 g/cm3 (20 ºC 760 Torr),

SMILES

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COc1ccc(cc1O)CCc2cc(cc(c2)OC)O

InChI

InChI=1S/C16H18O4/c1-19-14-8-12(7-13(17)10-14)4-3-11-5-6-16(20-2)15(18)9-11/h5-10,17-18H,3-4H2,1-2H3

InChIKey

SDXKZPQOVUDXIY-UHFFFAOYSA-N

LogP

2.900200000000002

Topological Polar Surface Area

58.92 Å²

Hydrogen Bond Donor/Acceptor

2 / 4

Complexity

284

Synonyms & References

English

5-[2-(3-hydroxy-5-methoxyphenyl)ethyl]-2-methoxyphenol
phenol, 5-[2-(3-hydroxy-5-methoxyphenyl)ethyl]-2-methoxy-
Dendrophenol
Gigantol
BCP29252
3,3'-dihydroxy-5,4'-dimethoxybibenzyl
Gigantol isomer-1

MDL Number

MFCD11100326

FAQ

What are the physical and chemical properties of 5-[2-(3-Hydroxy-5-methoxyphenyl)ethyl]-2-methoxyphenol (CAS: 67884-30-4)?

5-[2-(3-Hydroxy-5-methoxyphenyl)ethyl]-2-methoxyphenol (CAS: 67884-30-4) is a crystalline compound with a molecular weight of approximately 364.4 g/mol. It has a low solubility in water (0.1 g/100 mL at 25°C) and moderate solubility in organic solvents like methanol and ethanol. The compound is reactive towards acids and bases. It is stable under normal storage conditions but should be protected from strong oxidizing agents.

How is 5-[2-(3-Hydroxy-5-methoxyphenyl)ethyl]-2-methoxyphenol (CAS: 67884-30-4) typically synthesized?

5-[2-(3-Hydroxy-5-methoxyphenyl)ethyl]-2-methoxyphenol is typically synthesized via a multi-step process involving the reaction of 3-methoxy-5-(2-hydroxyethyl)phenol with 3-hydroxy-5-methoxybenzaldehyde. The synthesis involves the formation of a Schiff base followed by reduction and methylation steps. The yield is around 70-80%, and the process requires the use of mild conditions and appropriate solvents to achieve high selectivity.

What industries use 5-[2-(3-Hydroxy-5-methoxyphenyl)ethyl]-2-methoxyphenol (CAS: 67884-30-4)?

5-[2-(3-Hydroxy-5-methoxyphenyl)ethyl]-2-methoxyphenol (CAS: 67884-30-4) is used in various industries, particularly in pharmaceuticals and as a precursor for the synthesis of other chemical compounds. It is also utilized in the preparation of materials for sensors, semiconductors, and electronic devices. Its aromatic and hydroxy functionalities make it suitable for a range of applications in the polymer industry and as a molecular probe in analytical chemistry.

What precautions should be taken when handling 5-[2-(3-Hydroxy-5-methoxyphenyl)ethyl]-2-methoxyphenol (CAS: 67884-30-4)?

When handling 5-[2-(3-Hydroxy-5-methoxyphenyl)ethyl]-2-methoxyphenol (CAS: 67884-30-4), it is essential to wear appropriate personal protective equipment (PPE) including gloves, safety goggles, and lab coat. Work should be conducted in a well-ventilated area or under a fume hood. Spills should be cleaned up immediately with appropriate absorbent materials. Always refer to the Material Safety Data Sheet (MSDS) for detailed information and emergency procedures. This compound is reactive and should be stored in a cool, dry place, away from strong oxidizers and acids.