Cyclopropyl 5-bromo-2-chlorobenzamide

Basic Information

View in Editor

CAS Number

669734-35-4

Molecular Formula

C10H9BrClNO

Molecular Weight

274.55 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Fine Chemicals Dyes and Pigments Organic Dyes

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

SMILES

View in Editor

C1CC1NC(=O)C2=C(C=CC(=C2)Br)Cl

InChI

InChI=1S/C10H9BrClNO/c11-6-1-4-9(12)8(5-6)10(14)13-7-2-3-7/h1,4-5,7H,2-3H2,(H,13,14)

InChIKey

HVXQTKXSRJBMDT-UHFFFAOYSA-N

LogP

2.994700000000001

Topological Polar Surface Area

29.1 Å²

Hydrogen Bond Donor/Acceptor

1 / 2

Complexity

232

Synonyms & References

English

DTXSID70406570
SCHEMBL662706
AKOS001146316
CYCLOPROPYL 5-BROMO-2-CHLOROBENZAMIDE
5-bromo-2-chloro-n~1~-cyclopropylbenzamide
HVXQTKXSRJBMDT-UHFFFAOYSA-N
CS-0454755
Z30841107
A867356
5-Bromo-2-chloro-N-cyclopropyl-benzamide
MFCD04226747
EN300-7379630
AS-43687
5-bromo-2-chloro-N-cyclopropylbenzamide
669734-35-4
5-Bromo-2-chloro-N-cyclopropylbenzamide
Cyclopropyl 5-bromo-2-chlorobenzamide
AC1NIJSY
ACMC-209nx6
CTK5C5477
SureCN662706

MDL Number

MFCD04226747

FAQ

What are the physical and chemical properties of Cyclopropyl 5-bromo-2-chlorobenzamide (CAS: 669734-35-4)?

Cyclopropyl 5-bromo-2-chlorobenzamide (CAS: 669734-35-4) is a crystalline solid with a molecular weight of approximately 284.03 g/mol. It has a low solubility in water but is more soluble in organic solvents such as ethanol and acetone. The compound is relatively stable but can react with strong bases. It is prone to hydrolysis and has limited reactivity under normal conditions.

How is Cyclopropyl 5-bromo-2-chlorobenzamide (CAS: 669734-35-4) typically synthesized?

Cyclopropyl 5-bromo-2-chlorobenzamide can be synthesized through a multi-step reaction involving the bromination and chlorination of a benzene ring, followed by the amidation of the resulting compound with cyclopropylamine. The reaction typically requires the use of reagents like N-bromosuccinimide (NBS) and N-chlorosuccinimide (NCS) as catalysts. The yield and selectivity can be enhanced with careful control of reaction conditions and the use of appropriate solvents.

What industries use Cyclopropyl 5-bromo-2-chlorobenzamide (CAS: 669734-35-4)?

Cyclopropyl 5-bromo-2-chlorobenzamide (CAS: 669734-35-4) is used in the pharmaceutical and chemical industries for the development of novel compounds with specific functional groups. It may find applications in the synthesis of intermediates for drug development, as well as in materials science for the preparation of advanced polymers and other specialized chemicals.

What precautions should be taken when handling Cyclopropyl 5-bromo-2-chlorobenzamide (CAS: 669734-35-4)?

When handling Cyclopropyl 5-bromo-2-chlorobenzamide (CAS: 669734-35-4), it is essential to wear protective equipment such as gloves, goggles, and a lab coat. The compound should be stored in a cool, dry place away from direct sunlight and sources of heat. Handling should be done in a well-ventilated area or a fume hood to minimize exposure to vapors. In case of a spill, it is recommended to use appropriate containment and clean-up procedures as outlined in the safety data sheet (SDS).