6-hydroxy-5-nitro-pyridine-3-carboxylic acid

Basic Information

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CAS Number

6635-31-0

Molecular Formula

C6H4N2O5

Molecular Weight

184.11 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Melting Point

291°C

Boiling Point

463.4℃ at 760 mmHg

Density

1.7

Flash Point

173.7℃

SMILES

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C1=C(C(=O)NC=C1C(=O)O)[N+](=O)[O-]

InChI

InChI=1S/C6H4N2O5/c9-5-4(8(12)13)1-3(2-7-5)6(10)11/h1-2H,(H,7,9)(H,10,11)

InChIKey

VJMXJGVEVASJOD-UHFFFAOYSA-N

LogP

0.91680

Complexity

349

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

6-Hydroxy-5-nitronicotinicacid
NSC-52204
AC-24948
GS-6144
FT-0648943
EN300-139034
Z1198171772
SB12054
VJMXJGVEVASJOD-UHFFFAOYSA-N
6-HYDROXY-5-NITRO NICOTINIC ACID
6-hydroxy-5-nitronicotinic acid
AMY18607
J-518789
SY006707
F2147-0229
3-Pyridinecarboxylic acid, 1,6-dihydro-5-nitro-6-oxo-
A8950
6-Hydroxy-5-nitropyridine-3-carboxylic acid, 97%
5-NITRO-6-OXO-1,6-DIHYDRO-PYRIDINE-3-CARBOXYLIC ACID
6hydroxy-5-nitronicotinic acid
AKOS000265228
SCHEMBL2637045
CX1103
5-nitro-6-oxo-1,6-dihydropyridine-3-carboxylic acid
5-nitro-6-oxo-1H-pyridine-3-carboxylic acid
DTXSID70287689
6-Hydroxy-5-nitro-3-pyridinecarboxylic Acid
AKOS005255267
6-hydroxy-5-nitropyridine-3-carboxylic acid
6-Hydroxy-5-nitro-nicotinic acid
5-nitro-6-oxo-1,6-dihydro-3-pyridinecarboxylic acid

MDL Number

MFCD02180840

Customs Code

2933399090

FAQ

What are the physical and chemical properties of 6-hydroxy-5-nitro-pyridine-3-carboxylic acid (CAS: 6635-31-0)?

6-hydroxy-5-nitro-pyridine-3-carboxylic acid (CAS: 6635-31-0) is a crystalline solid with a molecular weight of approximately 217.08 g/mol. It has a solubility of about 0.019 g/100 mL in water at 20°C. Chemically, it is highly reactive, particularly with reducing agents and bases. It decomposes above 150°C and is sensitive to moisture and air oxidation.

How is 6-hydroxy-5-nitro-pyridine-3-carboxylic acid (CAS: 6635-31-0) typically synthesized?

6-hydroxy-5-nitro-pyridine-3-carboxylic acid (CAS: 6635-31-0) is typically synthesized through the nitration of 6-hydroxypyridine-3-carboxylic acid, followed by a selective reduction of the nitro group. The reaction can be catalyzed by concentrated sulfuric acid, and the yield can range from 70% to 85% depending on the reaction conditions and purification methods.

What industries use 6-hydroxy-5-nitro-pyridine-3-carboxylic acid (CAS: 6635-31-0)?

6-hydroxy-5-nitro-pyridine-3-carboxylic acid (CAS: 6635-31-0) is used in the pharmaceutical industry for the synthesis of certain medicinals and in the chemical industry for the development of sensors and semiconductors. It is also explored in the polymer industry for the production of specific polymers and composites.

What precautions should be taken when handling 6-hydroxy-5-nitro-pyridine-3-carboxylic acid (CAS: 6635-31-0)?

When handling 6-hydroxy-5-nitro-pyridine-3-carboxylic acid (CAS: 6635-31-0), it is essential to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. Handle it in a well-ventilated area or a fume hood to avoid inhalation. Spills should be cleaned up with caution, using appropriate absorbents, and disposed of according to local regulations. Refer to the safety data sheet (SDS) for detailed handling and storage instructions.