6-hydroxy-5-nitro-pyridine-3-carboxylic acid(CAS: 6635-31-0)

6-hydroxy-5-nitro-pyridine-3-carboxylic acid (CAS: 6635-31-0) is a crystalline solid with a molecular weight of approximately 217.08 g/mol. It has a solubility of about 0.019 g/100 mL in water at 20°C. Chemically, it is highly reactive, particularly with reducing agents and bases. It decomposes above 150°C and is sensitive to moisture and air oxidation.

6-hydroxy-5-nitro-pyridine-3-carboxylic acid (CAS: 6635-31-0) is typically synthesized through the nitration of 6-hydroxypyridine-3-carboxylic acid, followed by a selective reduction of the nitro group. The reaction can be catalyzed by concentrated sulfuric acid, and the yield can range from 70% to 85% depending on the reaction conditions and purification methods.

6-hydroxy-5-nitro-pyridine-3-carboxylic acid (CAS: 6635-31-0) is used in the pharmaceutical industry for the synthesis of certain medicinals and in the chemical industry for the development of sensors and semiconductors. It is also explored in the polymer industry for the production of specific polymers and composites.

When handling 6-hydroxy-5-nitro-pyridine-3-carboxylic acid (CAS: 6635-31-0), it is essential to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. Handle it in a well-ventilated area or a fume hood to avoid inhalation. Spills should be cleaned up with caution, using appropriate absorbents, and disposed of according to local regulations. Refer to the safety data sheet (SDS) for detailed handling and storage instructions.