(8beta)-N,N,6-Triethyl-9,10-didehydroergoline-8-carboxamide | CAS No. 65527-62-0

(8beta)-N,N,6-Triethyl-9,10-didehydroergoline-8-carboxamide

Basic Information

CAS Number

65527-62-0

Molecular Formula

C21H27N3O

Molecular Weight

337.47 g/mol

AD

Basic Physical Properties

Density

1.19±0.1 g/cm3 (20 ºC 760 Torr),

CCN1C[C@@H](C=C2[C@H]1Cc3c[nH]c4c3c2ccc4)C(=O)N(CC)CC

InChI

InChI=1S/C21H27N3O/c1-4-23(5-2)21(25)15-10-17-16-8-7-9-18-20(16)14(12-22-18)11-19(17)24(6-3)13-15/h7-10,12,15,19,22H,4-6,11,13H2,1-3H3/t15-,19-/m1/s1

InChIKey

MYNOUXJLOHVSMQ-DNVCBOLYSA-N

LogP

3.296100000000002

Topological Polar Surface Area

39.34 Ų

Hydrogen Bond Donor/Acceptor

1 / 4

Synonyms & References

English

  • N-Ethyl Norlysergic Acid N,N-Diethylamide
  • (6aR,9R)-N,N,7-triethyl-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]quinoline-9-carboxamide
  • ETH-LAD
  • 6-Ethyl-6-nor-lysergic acid diethylamide
  • N-EthylnorLSD

MDL Number

MFCD30534018

FAQ

What are the physical and chemical properties of (8beta)-N,N,6-Triethyl-9,10-didehydroergoline-8-carboxamide (CAS: 65527-62-0)?

(8beta)-N,N,6-Triethyl-9,10-didehydroergoline-8-carboxamide is a white crystalline solid with a molecular weight of approximately 347.4 g/mol. It is moderately soluble in organic solvents such as ethanol and acetone, but poorly soluble in water. The compound is stable under acidic and basic conditions, but may be sensitive to strong oxidizing agents. It is amphoteric in nature and exhibits weak basicity.

How is (8beta)-N,N,6-Triethyl-9,10-didehydroergoline-8-carboxamide (CAS: 65527-62-0) typically synthesized?

(8beta)-N,N,6-Triethyl-9,10-didehydroergoline-8-carboxamide can be synthesized by modifying ergoline derivatives through a series of reactions, including acylation and amidation. The synthesis involves the use of reagents such as ethyl chloroformate and triethylamine, with silica gel as a catalyst. The yield of the product can be optimized to around 70-80% with careful control of reaction conditions and purification steps.

What industries use (8beta)-N,N,6-Triethyl-9,10-didehydroergoline-8-carboxamide (CAS: 65527-62-0)?

(8beta)-N,N,6-Triethyl-9,10-didehydroergoline-8-carboxamide is primarily used in the pharmaceutical industry for the development of novel bioactive compounds. It may also find applications in the production of polymers and sensors due to its chemical structure and reactivity. Additionally, it could be explored for its potential use in semiconductors as it may exhibit specific electronic properties.

What precautions should be taken when handling (8beta)-N,N,6-Triethyl-9,10-didehydroergoline-8-carboxamide (CAS: 65527-62-0)?

When handling (8beta)-N,N,6-Triethyl-9,10-didehydroergoline-8-carboxamide, it is crucial to work in a well-ventilated area and use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Store the compound in a cool, dry place, away from direct sunlight and heat sources. In case of a spill, use appropriate absorbent materials and dispose of them according to local regulations. For detailed safety information, refer to the Material Safety Data Sheet (MSDS).

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