How is (8beta)-N,N,6-Triethyl-9,10-didehydroergoline-8-carboxamide (CAS: 65527-62-0) typically synthesized?

(8beta)-N,N,6-Triethyl-9,10-didehydroergoline-8-carboxamide can be synthesized by modifying ergoline derivatives through a series of reactions, including acylation and amidation. The synthesis involves the use of reagents such as ethyl chloroformate and triethylamine, with silica gel as a catalyst. The yield of the product can be optimized to around 70-80% with careful control of reaction conditions and purification steps.