(8beta)-N,N,6-Triethyl-9,10-didehydroergoline-8-carboxamide(CAS: 65527-62-0)

(8beta)-N,N,6-Triethyl-9,10-didehydroergoline-8-carboxamide is a white crystalline solid with a molecular weight of approximately 347.4 g/mol. It is moderately soluble in organic solvents such as ethanol and acetone, but poorly soluble in water. The compound is stable under acidic and basic conditions, but may be sensitive to strong oxidizing agents. It is amphoteric in nature and exhibits weak basicity.

(8beta)-N,N,6-Triethyl-9,10-didehydroergoline-8-carboxamide can be synthesized by modifying ergoline derivatives through a series of reactions, including acylation and amidation. The synthesis involves the use of reagents such as ethyl chloroformate and triethylamine, with silica gel as a catalyst. The yield of the product can be optimized to around 70-80% with careful control of reaction conditions and purification steps.

(8beta)-N,N,6-Triethyl-9,10-didehydroergoline-8-carboxamide is primarily used in the pharmaceutical industry for the development of novel bioactive compounds. It may also find applications in the production of polymers and sensors due to its chemical structure and reactivity. Additionally, it could be explored for its potential use in semiconductors as it may exhibit specific electronic properties.

When handling (8beta)-N,N,6-Triethyl-9,10-didehydroergoline-8-carboxamide, it is crucial to work in a well-ventilated area and use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Store the compound in a cool, dry place, away from direct sunlight and heat sources. In case of a spill, use appropriate absorbent materials and dispose of them according to local regulations. For detailed safety information, refer to the Material Safety Data Sheet (MSDS).