ethyl 5-(4-fluorophenyl)-1,2-oxazole-3-carboxylate | CAS No. 640291-92-5
ethyl 5-(4-fluorophenyl)-1,2-oxazole-3-carboxylate
Basic Information
CAS Number
640291-92-5
Molecular Formula
C12H10FNO3
Molecular Weight
235.21 g/mol
AD
Chemical Classification
Basic Physical Properties
Synonyms & References
English
- ethyl 5-(4-fluorophenyl)isoxazole-3-carboxylate
- 3-(4-FLUORO-PHENYL)-ISOXAZOLE-5-CARBOXYLIC ACID ETHYL ESTER
- ETHYL-5-(4-FLUOROPHENYL)-ISOXAZOLE-3-CARBOXYLATE
- 3-Isoxazolecarboxylic acid, 5-(4-fluorophenyl)-, ethyl ester
- Ethyl 5-(4-fluorophenyl)-1,2-oxazole-3-carboxylate
- LogP
MDL Number
MFCD08446405
FAQ
What are the physical and chemical properties of ethyl 5-(4-fluorophenyl)-1,2-oxazole-3-carboxylate (CAS: 640291-92-5)?
Ethyl 5-(4-fluorophenyl)-1,2-oxazole-3-carboxylate (CAS: 640291-92-5) is a crystalline solid with a molecular weight of approximately 250.23 g/mol. It is sparingly soluble in water but soluble in organic solvents like ethanol and acetonitrile. This compound exhibits good stability under normal conditions but reacts readily with strong oxidizing agents. Its melting point is around 150-155°C.
How is ethyl 5-(4-fluorophenyl)-1,2-oxazole-3-carboxylate (CAS: 640291-92-5) typically synthesized?
Ethyl 5-(4-fluorophenyl)-1,2-oxazole-3-carboxylate is typically synthesized via a multistep process involving the condensation of 4-fluorophenyl isocyanate with ethyl 1,2-oxazole-3-carboxylate. The reaction is usually carried out under mild conditions, utilizing a suitable catalyst to enhance yield and selectivity. The overall process provides good yields and is commonly performed in organic solvents.
What industries use ethyl 5-(4-fluorophenyl)-1,2-oxazole-3-carboxylate (CAS: 640291-92-5)?
Ethyl 5-(4-fluorophenyl)-1,2-oxazole-3-carboxylate (CAS: 640291-92-5) is primarily used in the pharmaceutical and chemical industries. It serves as a valuable intermediate in the synthesis of various drugs and is also used in the development of sensors and materials due to its unique chemical properties.
What precautions should be taken when handling ethyl 5-(4-fluorophenyl)-1,2-oxazole-3-carboxylate (CAS: 640291-92-5)?
When handling ethyl 5-(4-fluorophenyl)-1,2-oxazole-3-carboxylate (CAS: 640291-92-5), it is essential to use personal protective equipment (PPE) such as gloves, goggles, and a laboratory coat. The compound should be stored in a well-ventilated area and handled under a fume hood to minimize exposure. Proper spill cleanup procedures should be followed, and the Safety Data Sheet (SDS) should be consulted for detailed instructions.
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
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