ethyl 5-(4-fluorophenyl)-1,2-oxazole-3-carboxylate(CAS: 640291-92-5)

Ethyl 5-(4-fluorophenyl)-1,2-oxazole-3-carboxylate (CAS: 640291-92-5) is a crystalline solid with a molecular weight of approximately 250.23 g/mol. It is sparingly soluble in water but soluble in organic solvents like ethanol and acetonitrile. This compound exhibits good stability under normal conditions but reacts readily with strong oxidizing agents. Its melting point is around 150-155°C.

Ethyl 5-(4-fluorophenyl)-1,2-oxazole-3-carboxylate is typically synthesized via a multistep process involving the condensation of 4-fluorophenyl isocyanate with ethyl 1,2-oxazole-3-carboxylate. The reaction is usually carried out under mild conditions, utilizing a suitable catalyst to enhance yield and selectivity. The overall process provides good yields and is commonly performed in organic solvents.

Ethyl 5-(4-fluorophenyl)-1,2-oxazole-3-carboxylate (CAS: 640291-92-5) is primarily used in the pharmaceutical and chemical industries. It serves as a valuable intermediate in the synthesis of various drugs and is also used in the development of sensors and materials due to its unique chemical properties.

When handling ethyl 5-(4-fluorophenyl)-1,2-oxazole-3-carboxylate (CAS: 640291-92-5), it is essential to use personal protective equipment (PPE) such as gloves, goggles, and a laboratory coat. The compound should be stored in a well-ventilated area and handled under a fume hood to minimize exposure. Proper spill cleanup procedures should be followed, and the Safety Data Sheet (SDS) should be consulted for detailed instructions.