7-Acetamido-4-hydroxy-2-naphthalenesulfonic acid | CAS No. 6334-97-0

7-Acetamido-4-hydroxy-2-naphthalenesulfonic acid

Basic Information

CAS Number

6334-97-0

Molecular Formula

C12H11NO5S

Molecular Weight

281.29 g/mol

AD

Basic Physical Properties

Density

1.581

CC(=O)NC1=CC2=CC(=CC(=C2C=C1)O)S(=O)(=O)O

InChI

InChI=1S/C12H11NO5S/c1-7(14)13-9-2-3-11-8(4-9)5-10(6-12(11)15)19(16,17)18/h2-6,15H,1H3,(H,13,14)(H,16,17,18)

InChIKey

KKAMNIDZQVXDJV-UHFFFAOYSA-N

LogP

1.7504999999999995

Topological Polar Surface Area

103.69999999999999 Ų

Hydrogen Bond Donor/Acceptor

3 / 6

Complexity

444

Synonyms & References

English

  • NSC-7567
  • NSC 7567
  • 7-acetylamino-4-hydroxy-naphthalene-2-sulphonic acid
  • FT-0610927
  • AKOS015900279
  • CHEMBL1723728
  • 6334-97-0
  • SCHEMBL3481043
  • 2-Acetamido-5-hydroxy-7-naphthalenesulfonic acid
  • 7-acetamido-4-hydroxynaphthalene-2-sulfonic acid
  • NSC7567
  • 7-(Acetylamino)-4-hydroxy-2-naphthalenesulfonic acid
  • 7-Acetamido-4-hydroxynaphthalene-2-sulphonic acid
  • EINECS 228-715-5
  • 2-Naphthalenesulfonic acid, 7-acetamido-4-hydroxy-
  • MFCD00800454
  • DTXSID6064242
  • HMS3093C24
  • 7-Acetamido-4-hydroxy-naphthalene-2-sulfonic acid
  • NS00035420
  • GEO-04013
  • 7-(acetylamino)-4-hydroxy-2-Naphthalenesulfonicacid
  • 2-Acetamido-5-naphthol-7-sulfonicacid
  • 2-Naphthalenesulfonic acid, 7-(acetylamino)-4-hydroxy-
  • 2-Acetylamino-5-hydroxy-7-naphthalenesulfonic acid
  • MLS002638017
  • SMR001547520
  • 2-acetamido-5-hydroxy-7-naphthalenesulfonic acid
  • 2-Acetamido-5-naphthol-7-sufonic acid (Acetyl J acid)
  • 2-Acetoamido-5-Naphthol-7-Sulfonic Acid
  • Aceto J Acid

MDL Number

MFCD00800454

Customs Code

2924299090

FAQ

What are the physical and chemical properties of 7-Acetamido-4-hydroxy-2-naphthalenesulfonic acid (CAS: 6334-97-0)?

7-Acetamido-4-hydroxy-2-naphthalenesulfonic acid (CAS: 6334-97-0) is a crystalline solid with a molecular weight of approximately 308.27 g/mol. It is moderately soluble in water and ethanol. The compound is known for its reactivity towards nucleophiles and its ability to form complexes with various metal ions. It has an acidic nature due to the sulfonic acid group and a hydroxyl group which can participate in hydrogen bonding.

How is 7-Acetamido-4-hydroxy-2-naphthalenesulfonic acid (CAS: 6334-97-0) typically synthesized?

7-Acetamido-4-hydroxy-2-naphthalenesulfonic acid is typically synthesized by the sulfonation of 7-acetamido-4-hydroxy-2-naphthoic acid using fuming sulfuric acid in the presence of a catalyst such as aluminum sulfate. The reaction involves the introduction of a sulfonic acid group on the naphthalene ring, followed by the removal of the hydroxyl group to form the sulfonic acid salt. High yield and good selectivity are achieved under controlled conditions.

What industries use 7-Acetamido-4-hydroxy-2-naphthalenesulfonic acid (CAS: 6334-97-0)?

7-Acetamido-4-hydroxy-2-naphthalenesulfonic acid is used in various industries, including pharmaceuticals, where it serves as a precursor for the synthesis of other compounds. It is also utilized in the production of dyes and pigments, and in the development of sensors and semiconductors. Its applications in polymers and materials science are also expanding due to its unique functional groups.

What precautions should be taken when handling 7-Acetamido-4-hydroxy-2-naphthalenesulfonic acid (CAS: 6334-97-0)?

Proper handling of 7-Acetamido-4-hydroxy-2-naphthalenesulfonic acid (CAS: 6334-97-0) requires the use of personal protective equipment (PPE) such as gloves, safety goggles, and laboratory coats. Spills should be cleaned up by neutralizing with a suitable base and disposing of the material according to local regulations. It is also recommended to work in a well-ventilated area or a fume hood to minimize inhalation risks. Always refer to the Safety Data Sheet (SDS) for specific handling instructions.

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