3-nitro-1H-pyridin-2-one

Basic Information

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CAS Number

6332-56-5

Molecular Formula

C5H4N2O3

Molecular Weight

140.1 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Water Treatment Chemicals Coagulants and Flocculants Inorganic Coagulants

Basic Physical Properties

Physical State

Solid

Melting Point

224.0 to 228.0 deg-C

Boiling Point

368.8℃ at 760 mmHg

Density

1.5657 (rough estimate)

Flash Point

176.9℃

Refractive Index

1.4800 (estimate)

SMILES

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C1=CNC(=O)C(=C1)[N+](=O)[O-]

InChI

InChI=1S/C5H4N2O3/c8-5-4(7(9)10)2-1-3-6-5/h1-3H,(H,6,8)

InChIKey

BOAFCICMVMFLIT-UHFFFAOYSA-N

LogP

0.80630

Complexity

236

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Hazard Class

Class IRRITANT Class IRRITANT

Class IRRITANT-HARMFUL Class IRRITANT-HARMFUL

Synonyms & References

English

3-Nitro-2-pyridone
STR04579
AKOS001736337
SY004633
A807227
GS-6877
2-Hydroxy-3-nitropyridine, 98%
Pyridine, 2-hydroxy-3-nitro
NSC 26281
2-hydroxy-3-nitropyridin
AG-227/06235005
A8727
6332-56-5
FG-0494
AM20061396
EINECS 228-709-2
2-([(4-BROMOPHENYL)SULFONYL]AMINO)-4-METHYLPENTANOICACID
3-nitro-pyridin-2-ol
NSC-26281
8PJ
3-Nitro-2-pyridinol
3-Nitro-2-hydroxypyridine
3-Nitropyridin-2-ol
2(1H)-Pyridone, 3-nitro-
Z875018892
3-nitro-1,2-dihydropyridin-2-one
2-hydroxy-3-nitro pyridine
nitro-pyridinone
SCHEMBL244559
FT-0645797
W-104918

MDL Number

MFCD00006270

Customs Code

2933399090

FAQ

What are the physical and chemical properties of 3-nitro-1H-pyridin-2-one (CAS: 6332-56-5)?

3-nitro-1H-pyridin-2-one is a white to light yellow crystalline solid. Its molecular weight is approximately 171.11 g/mol. It is slightly soluble in water but soluble in organic solvents like methanol and dichloromethane. Chemically, it is a reactive compound, showing good reactivity towards nucleophiles and reducing agents.

How is 3-nitro-1H-pyridin-2-one (CAS: 6332-56-5) typically synthesized?

3-nitro-1H-pyridin-2-one can be synthesized via the nitration of 1H-pyridin-2-one. The nitration reaction is carried out using concentrated nitric acid and sulfuric acid as the nitrating mixture. The yield and selectivity can be optimized with careful control of reaction conditions such as temperature and stirring rate.

What industries use 3-nitro-1H-pyridin-2-one (CAS: 6332-56-5)?

3-nitro-1H-pyridin-2-one is used in the pharmaceutical industry for the synthesis of certain drugs. It also finds applications in the production of dyes, pigments, and as a precursor in the chemical industry for the development of new materials. Additionally, it plays a role in the production of organic semiconductors and sensors.

What precautions should be taken when handling 3-nitro-1H-pyridin-2-one (CAS: 6332-56-5)?

When handling 3-nitro-1H-pyridin-2-one, it is essential to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated environment or a fume hood to minimize inhalation risks. Spills should be cleaned up using appropriate absorbents and disposed of according to local regulations. Always consult the Safety Data Sheet (SDS) for detailed handling instructions.