3-nitro-1H-pyridin-2-one(CAS: 6332-56-5)

3-nitro-1H-pyridin-2-one is a white to light yellow crystalline solid. Its molecular weight is approximately 171.11 g/mol. It is slightly soluble in water but soluble in organic solvents like methanol and dichloromethane. Chemically, it is a reactive compound, showing good reactivity towards nucleophiles and reducing agents.

3-nitro-1H-pyridin-2-one can be synthesized via the nitration of 1H-pyridin-2-one. The nitration reaction is carried out using concentrated nitric acid and sulfuric acid as the nitrating mixture. The yield and selectivity can be optimized with careful control of reaction conditions such as temperature and stirring rate.

3-nitro-1H-pyridin-2-one is used in the pharmaceutical industry for the synthesis of certain drugs. It also finds applications in the production of dyes, pigments, and as a precursor in the chemical industry for the development of new materials. Additionally, it plays a role in the production of organic semiconductors and sensors.

When handling 3-nitro-1H-pyridin-2-one, it is essential to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated environment or a fume hood to minimize inhalation risks. Spills should be cleaned up using appropriate absorbents and disposed of according to local regulations. Always consult the Safety Data Sheet (SDS) for detailed handling instructions.