Elcatonin | CAS No. 60731-46-6

Elcatonin

Basic Information

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CAS Number

60731-46-6

Molecular Formula

C148H244N42O47

Molecular Weight

3363.83 g/mol

EINECS

262-393-7

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Surfactants Anionic Surfactants

Polymers and Plastics Thermoplastics Polyolefins

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Density

1.49±0.1 g/cm3(Predicted)

SMILES

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NCCCCCC(NCC(NCC(NCC(NCC(N1[C@H](C(NCC(NCC(NCC(N[C@@H](CC)C(NCC(N[C@@H](C)C(NCC(N[C@@H]([C@@H](C)O)C(N2[C@H](C(N)=O)CCC2)=O)=O)=O)=O)=O)=O)=O)=O)=O)CCC1)=O)=O)=O)=O)=O

InChI

InChIKey

KATAIKUHYMLRRF-VFZOQDHUSA-N

LogP

-1.15300

Topological Polar Surface Area

479.1599999999999 Å²

Hydrogen Bond Donor/Acceptor

17 / 32

Synonyms & References

English

(aminosubericacid1,7)-eelcalcitonin
1-butanoicacid-26-l-asparticacid-27-l-valine-7-dicarbacalcitonin(salmon)
29-l-alanine-
(L-ALPHA-AMINOSUBERIC ACID1,7)-CALCITONIN (EEL)
ELCATONIN
ELCATONIN (EEL)
(DES CYS1,CYCLO (SER2-ASU7))-CALCITONIN (EEL) ACETATE SALT
CYCLO(-SER-ASN-LEU-SER-THR-ASU)-VAL-LEU-GLY-LYS-LEU-SER-GLN-GLU-LEU-HIS-LYS-LEU-GLN-THR-TYR-PRO-ARG-THR-ASP-VAL-GLY-ALA-GLY-THR-PRO-NH2
Elcatonin
(Des-Cys?00cyclo(Ser?-Asu?))-Calcitonin(eel)
(Des-Cys1,cyclo(Ser2-Asu7))-Calcitonin (eel)
(Des-Cys1,cyclo(Ser2-Asu7))-Calcitonin (eel), Elcatonin, (Asu1·7)-Calcitonin (eel)
Carbocalcitonin
Elcatonin Acetate
(Aminosuberic acid 1,7)-eel calcitonin
1,7-Dicarbacalcitonin (salmon),1-butanoic acid-26-L-aspartic acid-27-L-valine-29-L-alanine
1,7-Dicarbacalcitonin,1-butanoic acid-26-L-aspartic acid-27-L-valine-29-L-alanine
EINECS 262-393-7
Elcatonina [INN-Spanish]
Elcatonine [INN-French]
Elcatoninum [INN-Latin]
HC-58
1,7-Dicarbacalcitonin(salmon), 1-butanoic acid-26-L-aspartic acid-27-L-valine-29-L-alanine-
1,4,7,10,13,16-Hexaazacyclotricosane, cyclic peptide deriv.
1-Des-amino-1,7-dicarba-eel calcitonin
Calcinil
Carbicalcin
Elcitonin
Turbocalcin
[Aminosuberic acid1,7]-eel calcitonin
Carbocalcitonin or Elcatonin

MDL Number

MFCD00221767

EC Number

262-393-7

Customs Code

2937190090

FAQ

What are the physical and chemical properties of Elcatonin (CAS: 60731-46-6)?

Elcatonin is a polypeptide hormone. It has a molecular weight of approximately 5000 Da. Physically, it is a white to off-white crystalline powder. It is slightly soluble in water, with a solubility of about 1 mg/mL at 25°C. Chemically, it is relatively stable but can be hydrolyzed by acid or base. Elcatonin is known for its reactivity in basic conditions, making it important to maintain a neutral pH during storage and handling.

How is Elcatonin (CAS: 60731-46-6) typically synthesized?

Elcatonin is typically synthesized through solid-phase peptide synthesis (SPPS). The process involves stepwise addition of protected amino acids to a growing peptide chain on a solid support. Commonly used protecting groups include Fmoc (Fluorenylmethoxycarbonyl) and Boc ( tert-Butyloxycarbonyl). The final product is then cleaved from the resin and purified using HPLC. This method ensures high purity and selectivity of the final product.

What industries use Elcatonin (CAS: 60731-46-6)?

Elcatonin is primarily used in the pharmaceutical industry for its potential therapeutic effects, particularly in the treatment of osteoporosis and bone disorders. It is also explored in biomedical research for its role in bone metabolism and wound healing. Additionally, Elcatonin has applications in the development of biosensors for detecting calcium ions, which are crucial in various biological processes.

What precautions should be taken when handling Elcatonin (CAS: 60731-46-6)?

When handling Elcatonin, it is essential to wear appropriate personal protective equipment (PPE), including gloves and safety goggles. Work should be conducted in a well-ventilated area or a fume hood to minimize inhalation risks. Spills should be immediately cleaned up using appropriate absorbents and following proper disposal procedures as outlined in the Safety Data Sheet (SDS). Always refer to the SDS for specific handling instructions and emergency protocols.