Elcatonin(CAS: 60731-46-6)

Elcatonin is a polypeptide hormone. It has a molecular weight of approximately 5000 Da. Physically, it is a white to off-white crystalline powder. It is slightly soluble in water, with a solubility of about 1 mg/mL at 25°C. Chemically, it is relatively stable but can be hydrolyzed by acid or base. Elcatonin is known for its reactivity in basic conditions, making it important to maintain a neutral pH during storage and handling.

Elcatonin is typically synthesized through solid-phase peptide synthesis (SPPS). The process involves stepwise addition of protected amino acids to a growing peptide chain on a solid support. Commonly used protecting groups include Fmoc (Fluorenylmethoxycarbonyl) and Boc ( tert-Butyloxycarbonyl). The final product is then cleaved from the resin and purified using HPLC. This method ensures high purity and selectivity of the final product.

Elcatonin is primarily used in the pharmaceutical industry for its potential therapeutic effects, particularly in the treatment of osteoporosis and bone disorders. It is also explored in biomedical research for its role in bone metabolism and wound healing. Additionally, Elcatonin has applications in the development of biosensors for detecting calcium ions, which are crucial in various biological processes.

When handling Elcatonin, it is essential to wear appropriate personal protective equipment (PPE), including gloves and safety goggles. Work should be conducted in a well-ventilated area or a fume hood to minimize inhalation risks. Spills should be immediately cleaned up using appropriate absorbents and following proper disposal procedures as outlined in the Safety Data Sheet (SDS). Always refer to the SDS for specific handling instructions and emergency protocols.