5-Nitroquinoline

Basic Information

View in Editor

CAS Number

607-34-1

Molecular Formula

C9H6N2O2

Molecular Weight

174.16 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Melting Point

70.0 to 73.0 deg-C

Boiling Point

323.1℃ at 760 mmHg

Density

1.2190 (estimate)

Flash Point

149.2℃

Refractive Index

1.6820 (rough estimate)

SMILES

View in Editor

C1=CC2=C(C=CC=N2)C(=C1)[N+](=O)[O-]

InChI

InChI=1S/C9H6N2O2/c12-11(13)9-5-1-4-8-7(9)3-2-6-10-8/h1-6H

InChIKey

NDDZXHOCOKCNBM-UHFFFAOYSA-N

LogP

2.66620

Complexity

202

Safety Information

View Safety Information

GHS Hazard Pictograms

H302

H312

H332

H351

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H312 Harmful in contact with skin
Acute toxicity, dermal

H332 Harmful if inhaled
Acute toxicity, inhalation

H351 Suspected of causing cancer
Carcinogenicity

Synonyms & References

English

QUINOLINE, 5-NITRO-
5-Nitroquinoline
AC-2880
PS-4966
SMR000342863
EN300-54168
InChI=1/C9H6N2O2/c12-11(13)9-5-1-4-8-7(9)3-2-6-10-8/h1-6
NITROQUINOLINE, 5-
607-34-1
NS00034440
NCGC00246158-01
N0344
CHEMBL164449
SB67468
AKOS000280794
NSC 65583
DTXSID8075255
MLS000516667
NCIOpen2_000225
4lm1
Oprea1_498855
SCHEMBL827685
F8889-5729
SY003219
FT-0620720
XHP5J23AZ5
5-Nitro-1-azanaphthalene
W-105231
EINECS 210-134-3
5-20-07-00325 (Beilstein Handbook Reference)
UNII-XHP5J23AZ5

MDL Number

MFCD00006790

FAQ

What are the physical and chemical properties of 5-Nitroquinoline (CAS: 607-34-1)?

5-Nitroquinoline (CAS: 607-34-1) has a crystalline form with a molecular weight of 179.07 g/mol. It is slightly soluble in water but soluble in most organic solvents. Chemically, it is moderately reactive, particularly towards reducing agents and nucleophiles. It exhibits basic properties due to the presence of an imine group.

How is 5-Nitroquinoline (CAS: 607-34-1) typically synthesized?

5-Nitroquinoline (CAS: 607-34-1) is typically synthesized through the nitration of quinoline. This involves treating quinoline with a nitronium ion source in the presence of a suitable catalyst. Common methods include using fuming nitric acid or nitronium tetraoxide. The reaction is exothermic and should be carried out cautiously to prevent excessive heating and decomposition.

What industries use 5-Nitroquinoline (CAS: 607-34-1)?

5-Nitroquinoline (CAS: 607-34-1) finds applications in pharmaceuticals, where it serves as a precursor for drug synthesis. It is also used in the production of dyes and pigments. Additionally, it plays a role in the development of sensors and semiconductors due to its unique optical and electronic properties.

What precautions should be taken when handling 5-Nitroquinoline (CAS: 607-34-1)?

When handling 5-Nitroquinoline (CAS: 607-34-1), it is crucial to use appropriate personal protective equipment (PPE) such as gloves, goggles, and lab coats. Work should be conducted in a well-ventilated area, preferably in a fume hood. Spills should be cleaned up immediately using appropriate materials, and the area should be thoroughly decontaminated. Always refer to the safety data sheet (SDS) for detailed information on handling and storage.