Alizapride HCl

Basic Information

View in Editor

CAS Number

59338-87-3

Molecular Formula

C16H22ClN5O2

Molecular Weight

351.84 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

207-210°C

SMILES

View in Editor

COC1=CC2=C(C=C1C(=O)NCC3CCCN3CC=C)NN=N2.Cl

InChI

InChI=1S/C16H21N5O2.ClH/c1-3-6-21-7-4-5-11(21)10-17-16(22)12-8-13-14(19-20-18-13)9-15(12)23-2;/h3,8-9,11H,1,4-7,10H2,2H3,(H,17,22)(H,18,19,20);1H

InChIKey

BRECEDGYMYXGNF-UHFFFAOYSA-N

LogP

1.7684999999999995

Topological Polar Surface Area

83.14 Å²

Hydrogen Bond Donor/Acceptor

2 / 7

Complexity

433

Safety Information

View Safety Information

Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

MLS002153819
Limican
Alizapride HCl
AS-13010
6-methoxy-N-[(1-prop-2-enylpyrrolidin-2-yl)methyl]-2H-benzotriazole-5-carboxamide;hydrochloride
AKOS016010267
SMR001233188
BCP28720
Alizapride hydrochloride
alizapridehydrochloride
s4257
Vergentan
6-methoxy-N-[(1-prop-2-enylpyrrolidin-2-yl)methyl]-3H-benzotriazole-5-carboxamide;hydrochloride
N-((1-Allylpyrrolidin-2-yl)methyl)-6-methoxy-1H-benzo[d][1,2,3]triazole-5-carboxamide hydrochloride
CHEMBL1896987
NAUSILEN
SR-01000841210-2
SCHEMBL3764712
A869218
6-Methoxy-N-[(1-prop-2-enylpyrrolidin-2-yl)methyl]-2H-benzotriazole-5-carboxamide hydrochloride;Alizapride Hydrochloride
D07563
Plitican (TN)
CCG-220451
59338-87-3
SW198917-2
C16H22ClN5O2
SR-01000841210
6-Methoxy-N-[(1-prop-2-enylpyrrolidin-2-yl)methyl]-2H-benzotriazole-5-carboxamide hydrochloride
Alizapride Hydrochloride
ALIZAPRIDE,IN-HOUSE
Alipril hydrochloride

MDL Number

MFCD02183928

Customs Code

2933990090

FAQ

What are the physical and chemical properties of Alizapride HCl (CAS: 59338-87-3)?

Alizapride HCl is a crystalline compound with a molecular weight of approximately 342.79 g/mol. It is sparingly soluble in water and ethanol. Chemically, it is a selective 5-HT4 receptor antagonist. It is stable under normal storage conditions but should be protected from moisture and light.

How is Alizapride HCl (CAS: 59338-87-3) typically synthesized?

Alizapride HCl is synthesized through a multi-step process involving the amination of an intermediate compound with hydrochloric acid. The synthesis requires careful control of reaction conditions to achieve high selectivity and yield. Commonly used catalysts and reagents include sodium hydride and hydrochloric acid.

What industries use Alizapride HCl (CAS: 59338-87-3)?

Alizapride HCl is primarily used in the pharmaceutical industry as an antiemetic and a 5-HT4 receptor antagonist. It is also of interest in research for its potential applications in treating gastrointestinal disorders and other conditions.

What precautions should be taken when handling Alizapride HCl (CAS: 59338-87-3)?

When handling Alizapride HCl, it is essential to use appropriate personal protective equipment (PPE), including gloves and goggles, and to work in a well-ventilated area or fume hood. Spills should be immediately cleaned up using appropriate methods, and the material safety data sheet (MSDS) should be consulted for detailed safety information.