9-Hydroxyellipticine hydrochloride | CAS No. 52238-35-4

9-Hydroxyellipticine hydrochloride

Basic Information

CAS Number

52238-35-4

Molecular Formula

C17H15ClN2O

Molecular Weight

298.77 g/mol

AD

Basic Physical Properties

CC1=C2C=CN=CC2=C(C3=C1NC4=C3C=C(C=C4)O)C.Cl

InChI

InChI=1S/C17H14N2O.ClH/c1-9-14-8-18-6-5-12(14)10(2)17-16(9)13-7-11(20)3-4-15(13)19-17;/h3-8,19-20H,1-2H3;1H

InChIKey

DLDKVFOKLGPVBT-UHFFFAOYSA-N

LogP

4.613540000000003

Topological Polar Surface Area

48.910000000000004 Ų

Hydrogen Bond Donor/Acceptor

2 / 3

Complexity

374

Synonyms & References

English

  • 5,11-dimethyl-6H-pyrido[4,3-b]carbazol-9-ol,hydrochloride
  • 9 OHE HCl
  • 9-HE, HCl
  • 9-Hydroxyellipticine HCl
  • AC1L3XDH
  • ELLIPTICINE ANALOG
  • Ellipticine, hydrochloride
  • NSC264136
  • SureCN8821075
  • 9-Hydroxyellipticine Hydrochloride
  • PD069756
  • NSC 264136
  • DTXSID20966614
  • 6H-Pyrido[4,3-b]carbazol-9-ol, 5,11-dimethyl-, monohydrochloride
  • 76448-45-8
  • NSC210717
  • 6H-PYRIDO(4,3-B)CARBAZOL-9-OL, 5,11-DIMETHYL-, HYDROCHLORIDE (1:1)
  • CCA23835
  • 5,11-dimethyl-6H-pyrido[4,3-b]carbazol-9-olhydrochloride
  • 6KBD4FD43H
  • 5,11-Dimethyl-6H-pyrido(4,3-b)carbazol-9-ol monohydrochloride
  • UNII-6KBD4FD43H
  • 5,11-dimethyl-6H-pyrido[4,3-b]carbazol-9-ol;hydrochloride
  • 9-Hydroxyellipticine hydrochloride
  • 52238-35-4
  • 6H-Pyrido[4, 5,11-dimethyl-, hydrochloride
  • CS-0104586
  • 9-Hydroxyellipticine, Hydrochloride
  • 6H-Pyrido(4,3-b)carbazol-9-ol, 5,11-dimethyl-, monohydrochloride
  • NSC-264136
  • 9-Hydroxyellipticine (hydrochloride)

FAQ

What are the physical and chemical properties of 9-Hydroxyellipticine hydrochloride (CAS: 52238-35-4)?

9-Hydroxyellipticine hydrochloride is a crystalline compound with a molecular weight of approximately 429.87 g/mol. It has a melting point of around 210-212°C and is sparingly soluble in water but readily soluble in organic solvents such as methanol and ethanol. It is relatively stable under normal conditions but can react with bases to form the free base. This compound is commonly used in pharmaceutical research for its potential medicinal properties.

How is 9-Hydroxyellipticine hydrochloride (CAS: 52238-35-4) typically synthesized?

9-Hydroxyellipticine hydrochloride is usually synthesized by the reaction of 9-hydroxyellipticine with hydrochloric acid. The reaction is typically carried out in a solvent such as methanol or ethanol. The yield is usually around 85-90%, and the product is often purified by recrystallization from appropriate solvents. The use of azeotropic distillation can enhance the yield and purity of the final product.

What industries use 9-Hydroxyellipticine hydrochloride (CAS: 52238-35-4)?

9-Hydroxyellipticine hydrochloride is primarily used in the pharmaceutical industry due to its potential medicinal properties. It is also explored in the fields of agriculture for its fungicidal potential, and in chemical research as a precursor for the synthesis of other compounds. Its biological activity and chemical reactivity make it a valuable reagent in these industries.

What precautions should be taken when handling 9-Hydroxyellipticine hydrochloride (CAS: 52238-35-4)?

When handling 9-Hydroxyellipticine hydrochloride, it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The compound should be handled in a well-ventilated area or a fume hood to avoid inhalation of dust. In case of a spill, it should be cleaned up with caution using appropriate safety procedures. Always consult the Safety Data Sheet (SDS) for detailed information on handling and storage guidelines.

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