9-Hydroxyellipticine hydrochloride(CAS: 52238-35-4)

9-Hydroxyellipticine hydrochloride is a crystalline compound with a molecular weight of approximately 429.87 g/mol. It has a melting point of around 210-212°C and is sparingly soluble in water but readily soluble in organic solvents such as methanol and ethanol. It is relatively stable under normal conditions but can react with bases to form the free base. This compound is commonly used in pharmaceutical research for its potential medicinal properties.

9-Hydroxyellipticine hydrochloride is usually synthesized by the reaction of 9-hydroxyellipticine with hydrochloric acid. The reaction is typically carried out in a solvent such as methanol or ethanol. The yield is usually around 85-90%, and the product is often purified by recrystallization from appropriate solvents. The use of azeotropic distillation can enhance the yield and purity of the final product.

9-Hydroxyellipticine hydrochloride is primarily used in the pharmaceutical industry due to its potential medicinal properties. It is also explored in the fields of agriculture for its fungicidal potential, and in chemical research as a precursor for the synthesis of other compounds. Its biological activity and chemical reactivity make it a valuable reagent in these industries.

When handling 9-Hydroxyellipticine hydrochloride, it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The compound should be handled in a well-ventilated area or a fume hood to avoid inhalation of dust. In case of a spill, it should be cleaned up with caution using appropriate safety procedures. Always consult the Safety Data Sheet (SDS) for detailed information on handling and storage guidelines.