Methyl 3-chloro-2-hydroxybenzoate

Basic Information

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CAS Number

52159-67-8

Molecular Formula

C8H7ClO3

Molecular Weight

186.59 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Esters

Basic Chemical Raw Materials Organic Chemicals Ethers

Fine Chemicals Dyes and Pigments Organic Dyes

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

SMILES

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COC(=O)C1=C(C(=CC=C1)Cl)O

InChI

InChI=1S/C8H7ClO3/c1-12-8(11)5-3-2-4-6(9)7(5)10/h2-4,10H,1H3

InChIKey

MVXSDDGVZSEOIS-UHFFFAOYSA-N

LogP

1.8321999999999998

Topological Polar Surface Area

46.53 Å²

Hydrogen Bond Donor/Acceptor

1 / 3

Complexity

172

Synonyms & References

English

EN300-1615099
Benzoic acid, 3-chloro-2-hydroxy-, methyl ester
3V9LCX453D
A848117
AC-28688
FS-3137
3-Chloro-2-hydroxybenzoic acid methyl ester
52159-67-8
MFCD00128116
SY102484
DTXSID30200177
UNII-3V9LCX453D
Methyl 3-chlorosalicylate
Methyl3-chloro-2-hydroxybenzoate
NS00032436
EINECS 257-694-5
SCHEMBL2796868
CL8549
AKOS006271862
Methyl-3-Chloro-2-hydroxybenzoate
MVXSDDGVZSEOIS-UHFFFAOYSA-N
FT-0703921
METHYL M-CHLOROSALICYLATE
methyl 3-chloro-2-hydroxybenzoate
methyl-3-chloro-salicylate
CS-W006044
Methyl 3-chloro-2-hydroxybenzoate
Benzoic acid,3-chloro-2-hydroxy-, methyl ester
METHYL-3-CHLORO-2-HYDROXYBENZOATE
3-Chlor-2-hydroxy-benzoesaeure-methylester
3-chloro-2-hydroxy-benzoic acid methyl ester

MDL Number

MFCD00128116

Customs Code

2918290000

FAQ

What are the physical and chemical properties of Methyl 3-chloro-2-hydroxybenzoate (CAS: 52159-67-8)?

Methyl 3-chloro-2-hydroxybenzoate has a crystalline form with a molecular weight of approximately 219.58 g/mol. It is slightly soluble in water and has good solubility in common organic solvents like ethanol and acetone. The compound is moderately reactive, particularly with reagents that can introduce nucleophilic substitution or oxidation reactions.

How is Methyl 3-chloro-2-hydroxybenzoate (CAS: 52159-67-8) typically synthesized?

Methyl 3-chloro-2-hydroxybenzoate is typically synthesized via the esterification of 3-chloro-2-hydroxybenzoic acid with methanol in the presence of an acid catalyst such as sulfuric acid. The process involves heating the reaction mixture under reflux to achieve a high yield of the desired ester.

What industries use Methyl 3-chloro-2-hydroxybenzoate (CAS: 52159-67-8)?

Methyl 3-chloro-2-hydroxybenzoate is used in various industries, including pharmaceuticals, where it serves as a precursor for the synthesis of certain drugs. It is also used in the production of organic pigments and dyes, as a raw material in the chemical industry, and in the formulation of certain consumer products.

What precautions should be taken when handling Methyl 3-chloro-2-hydroxybenzoate (CAS: 52159-67-8)?

When handling Methyl 3-chloro-2-hydroxybenzoate, it is crucial to wear appropriate personal protective equipment, including gloves, goggles, and a lab coat. The compound should be stored in a dry, well-ventilated area, away from direct sunlight and heat sources. Spills should be cleaned up using appropriate chemical spill kits, and the area should be well-ventilated. Always refer to the Material Safety Data Sheet (MSDS) for detailed safety information.