(5alpha,17beta)-17-Hydroxyandrostan-3-one

Basic Information

View in Editor

CAS Number

521-18-6

Molecular Formula

C19H30O2

Molecular Weight

290.45 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ketones

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Melting Point

173-183 ºC

Boiling Point

372.52°C (rough estimate)

Flash Point

9℃

Refractive Index

1.4709 (estimate)

Specific Rotation

27 º

SMILES

View in Editor

C[C@]12CCC(=O)C[C@@H]1CC[C@@H]3[C@@H]2CC[C@]4([C@H]3CC[C@@H]4O)C

InChI

InChI=1S/C19H30O2/c1-18-9-7-13(20)11-12(18)3-4-14-15-5-6-17(21)19(15,2)10-8-16(14)18/h12,14-17,21H,3-11H2,1-2H3/t12-,14-,15-,16-,17-,18-,19-/m0/s1

InChIKey

NVKAWKQGWWIWPM-ABEVXSGRSA-N

LogP

3.959100000000003

Topological Polar Surface Area

37.3 Å²

Hydrogen Bond Donor/Acceptor

1 / 2

Complexity

459

Synonyms & References

English

Stanolone
-(5-alpha,17-beta)-17-hydroxyandrostan-3-one
(5alpha,17beta)-17-Hydroxy-androstan-3-one
17beta-Hydroxy-3-androstanone
17-beta-hydroxy-5-alpha-androstan-3-on
17-hydroxy-,(5-alpha,17-beta)-androstan-3-on
17-Hydroxyandrostan-3-one
5A-Androstan-3-on-17B-ol
5a-Androstan-3-one, 17beta-hydroxy-
5α-Androstan-17β-ol-3-one
5α-Dihydrotestosterone (DHT) solution
Androstanolone
Stanolone-D4
[14C]-Dihydrotestosterone
[3H]-Dihydrotestosterone
17beta-hydroxy-5alpha-androstan-3-one
Anaboleen
Anabolex
Andractim
Androlone
DHT
dihydrotestosterone
Neodrol
Protona
Stanaprol
Stanolon
Stanorone
5a-Dihydrotestosterone
5a-Androstan-17b-ol-3-one
17b-Hydroxy-5a-androstan-3-one
Testosterone EP Impurity F

MDL Number

MFCD00003667

FAQ

What are the physical and chemical properties of (5alpha,17beta)-17-Hydroxyandrostan-3-one (CAS: 521-18-6)?

(5alpha,17beta)-17-Hydroxyandrostan-3-one is a white crystalline powder with a molecular weight of approximately 282.43 g/mol. It is slightly soluble in water and more soluble in organic solvents like methanol and ethanol. This compound is known for its low reactivity under normal conditions but can undergo hydrolysis in the presence of strong acids or bases. It is commonly used in research and pharmaceutical applications due to its hormonal properties.

How is (5alpha,17beta)-17-Hydroxyandrostan-3-one (CAS: 521-18-6) typically synthesized?

(5alpha,17beta)-17-Hydroxyandrostan-3-one is typically synthesized through a series of reactions starting from androst-4-ene. A common method involves the reduction of androst-4-ene to androstan-4-ol, followed by a keto-reduction to form the final product. This synthesis often employs lithium aluminum hydride (LAH) as a reducing agent, with careful control of reaction conditions to ensure high yield and selectivity.

What industries use (5alpha,17beta)-17-Hydroxyandrostan-3-one (CAS: 521-18-6)?

(5alpha,17beta)-17-Hydroxyandrostan-3-one is primarily used in the pharmaceutical industry for hormone-related research and development. It is also utilized in the production of certain steroid and hormonal drugs. Additionally, this compound may have applications in the field of chemical sensors and as a reagent in organic synthesis.

What precautions should be taken when handling (5alpha,17beta)-17-Hydroxyandrostan-3-one (CAS: 521-18-6)?

When handling (5alpha,17beta)-17-Hydroxyandrostan-3-one, it is crucial to wear appropriate personal protective equipment (PPE), including gloves, safety goggles, and lab coats. Ensure the work is conducted in a well-ventilated area or under a fume hood. Spills should be cleaned up immediately, and care should be taken to avoid skin and eye contact. Always consult the Safety Data Sheet (SDS) for detailed handling and disposal instructions.