Compound Q&A
How is (5alpha,17beta)-17-Hydroxyandrostan-3-one (CAS: 521-18-6) typically synthesized?
Answer
(5alpha,17beta)-17-Hydroxyandrostan-3-one is typically synthesized through a series of reactions starting from androst-4-ene. A common method involves the reduction of androst-4-ene to androstan-4-ol, followed by a keto-reduction to form the final product. This synthesis often employs lithium aluminum hydride (LAH) as a reducing agent, with careful control of reaction conditions to ensure high yield and selectivity.
About
CAS No
521-18-6
English Name
(5alpha,17beta)-17-Hydroxyandrostan-3-one
Molecular Formula
C19H30O2
Molecular Weight
290.45 g/mol
SMILES
C[C@]12CCC(=O)C[C@@H]1CC[C@@H]3[C@@H]2CC[C@]4([C@H]3CC[C@@H]4O)C
InChIKey
NVKAWKQGWWIWPM-ABEVXSGRSA-N
Last Updated: 2025-10-05 08:54
