(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)acetic acid

Basic Information

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CAS Number

4702-13-0

Molecular Formula

C10H7NO4

Molecular Weight

205.17 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Melting Point

194.0 to 198.0 deg-C

Boiling Point

412.6°C at 760 mmHg

Flash Point

203.3℃

Refractive Index

1.5600 (estimate)

SMILES

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OC(=O)CN1C(=O)c2ccccc2C1=O

InChI

InChI=1S/C10H7NO4/c12-8(13)5-11-9(14)6-3-1-2-4-7(6)10(11)15/h1-4H,5H2,(H,12,13)

InChIKey

WQINSVOOIJDOLJ-UHFFFAOYSA-N

LogP

0.36720000000000014

Topological Polar Surface Area

74.68 Å²

Hydrogen Bond Donor/Acceptor

1 / 5

Complexity

301

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

1,3-Dihydro-1,3-dioxo-2H-isoindoleacetic acid
1,3-Dioxo-2-isoindolineacetic acid
N-Phthaloylglycine
Phthalimidoacetic acid
Phthaloyl glycine
(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)-acetic acid
N-Phthalylglycine
Phthaliminoacetic Acid
1,3-dihydro-1,3-dioxo-2H-isoindole-2-acetic acid
2-phthalimidoacetic acid
N-phtaloyl glycine
N-Phthalimidoacetic Acid
N-PHTHALOGLYCINE
n-phthalylglycin
PHT-GLY-OH
phthalimidomethylcarboxylic acid
Phthaloglycine
Phthaloyl-glycine
PHTHALYL GLYCINE
N-Phthaloylglycine;Phthalimidoacetic acid
Phthaloylglycine
N-(Carboxymethyl)phthalimide
N,N-Phthaloylglycine
2-(1,3-dioxoisoindolin-2-yl)acetic acid
(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)acetic acid
2H-Isoindole-2-acetic acid, 1,3-dihydro-1,3-dioxo-
2-ISOINDOLINEACETIC ACID, 1,3-DIOXO-
N-(Carboxymethyl)-phthalimide
1,3-Dihydro-1,3-dioxo-2
2-(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)acetic acid

MDL Number

MFCD00005900

FAQ

What are the physical and chemical properties of (1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)acetic acid (CAS: 4702-13-0)?

(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)acetic acid is a crystalline solid with a molecular weight of approximately 236.25 g/mol. It has a melting point of around 165-168°C and is slightly soluble in water. The compound is reactive under certain conditions, particularly in the presence of strong acids or bases. It displays good stability in air and is not particularly volatile.

How is (1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)acetic acid (CAS: 4702-13-0) typically synthesized?

(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)acetic acid is often synthesized via the condensation of 1,3-dioxo-1,3-dihydro-2H-isoindole-2-carboxaldehyde with acetic anhydride. The reaction is typically conducted in the presence of a catalyst to ensure high selectivity and yield. Commonly used solvents include dichloromethane or acetonitrile.

What industries use (1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)acetic acid (CAS: 4702-13-0)?

(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)acetic acid finds applications in pharmaceuticals, where it serves as a precursor in the synthesis of certain drugs. It is also used in the development of sensors for detecting specific compounds and in the production of certain polymers. Due to its unique chemical properties, it is explored in semiconductor applications for its potential role in material science.

What precautions should be taken when handling (1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)acetic acid (CAS: 4702-13-0)?

When handling (1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)acetic acid, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The compound should be stored in a well-ventilated area and handled in a fume hood to minimize exposure. Spills should be cleaned up using appropriate safety protocols, and the site should be decontaminated. Always refer to the safety data sheet (SDS) for detailed information on handling and storage.