3-(3-Nitrophenyl)pyridine

Basic Information

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CAS Number

4282-50-2

Molecular Formula

C11H8N2O2

Molecular Weight

200.19 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Melting Point

93-95 ºC

Boiling Point

363.513°C at 760 mmHg

Flash Point

173.647°C

Refractive Index

1.611

SMILES

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[O-][N+](=O)c1cccc(c1)c2cccnc2

InChI

InChI=1S/C11H8N2O2/c14-13(15)11-5-1-3-9(7-11)10-4-2-6-12-8-10/h1-8H

InChIKey

VNYZVWPHCFEYNE-UHFFFAOYSA-N

LogP

3.18000

Synonyms & References

English

3-(3-Nitrophenyl)pyridine
OR8952
3-(m-Nitrophenyl)pyridine

MDL Number

MFCD08543459

Customs Code

2933399090

FAQ

What are the physical and chemical properties of 3-(3-Nitrophenyl)pyridine (CAS: 4282-50-2)?

3-(3-Nitrophenyl)pyridine is a crystalline solid with a molecular weight of approximately 220.08 g/mol. It has a low solubility in water but is soluble in common organic solvents like dichloromethane and ethanol. This compound is relatively stable but can decompose under strong reducing conditions. It shows moderate reactivity towards nucleophiles and electrophiles.

How is 3-(3-Nitrophenyl)pyridine (CAS: 4282-50-2) typically synthesized?

3-(3-Nitrophenyl)pyridine is typically synthesized via electrophilic aromatic substitution. The reaction involves the nitration of 3-pyridylbenzene using nitric acid and sulfuric acid as the nitrating reagents. The yield is usually around 70-80%, and the reaction is carried out under mild conditions to ensure selectivity.

What industries use 3-(3-Nitrophenyl)pyridine (CAS: 4282-50-2)?

3-(3-Nitrophenyl)pyridine finds applications in pharmaceuticals, where it serves as a precursor for the synthesis of dyes and pigments. It is also used in the production of certain sensors and semiconductors due to its unique electronic properties.

What precautions should be taken when handling 3-(3-Nitrophenyl)pyridine (CAS: 4282-50-2)?

When handling 3-(3-Nitrophenyl)pyridine, it is essential to wear appropriate personal protective equipment (PPE), including gloves and safety goggles. Work should be conducted in a well-ventilated area or fume hood to avoid inhalation. Spills should be immediately cleaned up with water and appropriate absorbents. Always refer to the Safety Data Sheet (SDS) for detailed handling instructions.