2-Phenoxy-1-phenylethanol

Basic Information

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CAS Number

4249-72-3

Molecular Formula

C14H14O2

Molecular Weight

214.26 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Physical Properties

SMILES

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C1=CC=C(C=C1)C(COC2=CC=CC=C2)O

InChI

InChI=1S/C14H14O2/c15-14(12-7-3-1-4-8-12)11-16-13-9-5-2-6-10-13/h1-10,14-15H,11H2

InChIKey

GSBICRJXEDSPTE-UHFFFAOYSA-N

LogP

2.7990000000000017

Topological Polar Surface Area

29.46 Å²

Hydrogen Bond Donor/Acceptor

1 / 2

Complexity

181

Synonyms & References

English

CS-W006550
4249-72-3
A872875
DS-11559
C75138
AKOS008962568
2-Phenoxy-1-phenylethanol
MFCD09880900
BenzeneMethanol, alpha-(phenoxyMethyl)-
SCHEMBL1496496
2-Phenoxy-1-phenylethan-1-ol
Benzenemethanol, a-(phenoxymethyl)-
GSBICRJXEDSPTE-UHFFFAOYSA-N
AK318401
1-phenyl-2-phenoxyethanol
BC4123222

MDL Number

MFCD09880900

FAQ

What are the physical and chemical properties of 2-Phenoxy-1-phenylethanol (CAS: 4249-72-3)?

2-Phenoxy-1-phenylethanol (CAS: 4249-72-3) is a colorless liquid with a molecular weight of approximately 216.26 g/mol. It has a high boiling point of around 220°C and a density of 1.06 g/cm³. The compound is slightly soluble in water but miscible with common organic solvents. It exhibits moderate reactivity, particularly towards nucleophilic substitution reactions and can be oxidized under certain conditions.

How is 2-Phenoxy-1-phenylethanol (CAS: 4249-72-3) typically synthesized?

2-Phenoxy-1-phenylethanol is commonly synthesized via the condensation of phenoxyacetaldehyde with phenylmagnesium bromide followed by acid hydrolysis. The reaction typically proceeds under mild conditions using a catalytic amount of a strong acid like hydrochloric acid. The yield is generally above 70%, and the reaction is highly selective, providing a pure and stable product.

What industries use 2-Phenoxy-1-phenylethanol (CAS: 4249-72-3)?

2-Phenoxy-1-phenylethanol (CAS: 4249-72-3) finds application in various industries. It is used as a fragrance compound in the cosmetics and perfume industries due to its pleasant aroma. Additionally, it is utilized in the pharmaceutical industry as an intermediate in the synthesis of certain drugs. Its chemical properties also make it suitable for applications in polymer manufacturing and as a sensor component.

What precautions should be taken when handling 2-Phenoxy-1-phenylethanol (CAS: 4249-72-3)?

When handling 2-Phenoxy-1-phenylethanol (CAS: 4249-72-3), it is essential to use appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area, preferably in a fume hood, to minimize inhalation risks. Spills should be cleaned up using appropriate absorbent materials, and the area should be thoroughly ventilated until all traces of the compound are removed. Always consult the Material Safety Data Sheet (MSDS) for specific safety guidelines and emergency procedures.