Compound Q&A

How is 2-Phenoxy-1-phenylethanol (CAS: 4249-72-3) typically synthesized?

Answer

2-Phenoxy-1-phenylethanol
2-Phenoxy-1-phenylethanol is commonly synthesized via the condensation of phenoxyacetaldehyde with phenylmagnesium bromide followed by acid hydrolysis. The reaction typically proceeds under mild conditions using a catalytic amount of a strong acid like hydrochloric acid. The yield is generally above 70%, and the reaction is highly selective, providing a pure and stable product.

About

CAS No 4249-72-3
English Name 2-Phenoxy-1-phenylethanol
Molecular Formula C14H14O2
Molecular Weight 214.26 g/mol
SMILES C1=CC=C(C=C1)C(COC2=CC=CC=C2)O
InChIKey GSBICRJXEDSPTE-UHFFFAOYSA-N
Last Updated: 2025-10-31 20:53

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