Methyl 6-bromoimidazo[1,2-a]pyridine-2-carboxylate

Basic Information

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CAS Number

354548-08-6

Molecular Formula

C9H7BrN2O2

Molecular Weight

255.07 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Esters

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

SMILES

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COC(=O)C1=CN2C=C(C=CC2=N1)Br

InChI

InChI=1S/C9H7BrN2O2/c1-14-9(13)7-5-12-4-6(10)2-3-8(12)11-7/h2-5H,1H3

InChIKey

DCQQILZPUHSRGM-UHFFFAOYSA-N

LogP

1.8833999999999997

Topological Polar Surface Area

43.60000000000001 Å²

Hydrogen Bond Donor/Acceptor

0 / 4

Complexity

237

Synonyms & References

English

Methyl 6-bromoimidazo[1,2-a]pyridine-2-carboxylate
6-Bromoimidazo[1,2-a]pyridine-2-carboxylic acid methyl ester
methyl 6-bromoimidazo[1,2-a]pyridine-2-carboxylate
CS-0053760
DTXSID70583330
J-518432
PB26071
AL-182/11878001
DB-069211
6-Bromoimidazo[1,2-a]pyridine-2-carboxylic acid methyl ester, AldrichCPR
AKOS015852144
Oprea1_336847
Methyl6-bromoimidazo[1,2-a]pyridine-2-carboxylate
Methyl 6-bromoH-imidazo[1,2-a]pyridine-2-carboxylate
6-Bromoimidazo[1,2-a]pyridine-2-carboxylic acid methyl ester 98%
MFCD01648244
AMY25892
354548-08-6
SCHEMBL1553322
AS-40913
SY251241

MDL Number

MFCD01648244

FAQ

What are the physical and chemical properties of Methyl 6-bromoimidazo[1,2-a]pyridine-2-carboxylate (CAS: 354548-08-6)?

Methyl 6-bromoimidazo[1,2-a]pyridine-2-carboxylate (CAS: 354548-08-6) is a crystalline solid with a molecular weight of approximately 281.03 g/mol. It has a high solubility in polar organic solvents such as DMSO and moderate solubility in water. The compound is moderately reactive and can undergo substitution reactions. It is stable under normal laboratory conditions but should be stored away from strong bases and reducing agents.

How is Methyl 6-bromoimidazo[1,2-a]pyridine-2-carboxylate (CAS: 354548-08-6) typically synthesized?

Methyl 6-bromoimidazo[1,2-a]pyridine-2-carboxylate is typically synthesized through an aromatic substitution reaction. The synthesis involves bromination of methyl imidazo[1,2-a]pyridine-2-carboxylate under an appropriate catalytic system, with a yield of up to 85%. Common solvents include DMF, and the reaction is monitored by TLC or GC methods.

What industries use Methyl 6-bromoimidazo[1,2-a]pyridine-2-carboxylate (CAS: 354548-08-6)?

Methyl 6-bromoimidazo[1,2-a]pyridine-2-carboxylate (CAS: 354548-08-6) is used in the pharmaceutical industry for the development of potential drug candidates. It is also utilized in the sensor industry due to its reactivity and stability properties. Additionally, it may have applications in the synthesis of functional polymers and as a precursor in semiconductor manufacturing.

What precautions should be taken when handling Methyl 6-bromoimidazo[1,2-a]pyridine-2-carboxylate (CAS: 354548-08-6)?

When handling Methyl 6-bromoimidazo[1,2-a]pyridine-2-carboxylate (CAS: 354548-08-6), it is essential to wear appropriate personal protective equipment (PPE) including gloves, safety goggles, and a lab coat. The compound should be handled in a well-ventilated fume hood to avoid inhalation of fumes. Spills should be cleaned up with absorbent materials and disposed of according to local regulations. Always consult the Safety Data Sheet (SDS) for detailed handling and disposal procedures.