2-Methyl-2-propanyl [1-(4-chlorophenyl)cyclobutyl]carbamate | CAS No. 1032349-96-4

2-Methyl-2-propanyl [1-(4-chlorophenyl)cyclobutyl]carbamate

Basic Information

CAS Number

1032349-96-4

Molecular Formula

C15H20ClNO2

Molecular Weight

281.78 g/mol

AD

Basic Physical Properties

CC(C)(C)OC(=O)NC1(CCC1)C2=CC=C(C=C2)Cl

InChI

InChI=1S/C15H20ClNO2/c1-14(2,3)19-13(18)17-15(9-4-10-15)11-5-7-12(16)8-6-11/h5-8H,4,9-10H2,1-3H3,(H,17,18)

InChIKey

PSCUVXVVLMRGJY-UHFFFAOYSA-N

LogP

4.243900000000004

Topological Polar Surface Area

38.33 Ų

Hydrogen Bond Donor/Acceptor

1 / 3

Synonyms & References

English

  • Tert-butyl 1-(4-chlorophenyl)cyclobutylcarbamate
  • tert-butyl N-[1-(4-chlorophenyl)cyclobutyl]carbamate
  • 1-(boc-aMino)-1-(4-chlorophenyl)-cyclobutane
  • Carbamic acid, N-[1-(4-chlorophenyl)cyclobutyl]-, 1,1-dimethylethyl ester

MDL Number

MFCD21607231

Customs Code

2921499090

FAQ

What are the physical and chemical properties of 2-Methyl-2-propanyl [1-(4-chlorophenyl)cyclobutyl]carbamate (CAS: 1032349-96-4)?

2-Methyl-2-propanyl [1-(4-chlorophenyl)cyclobutyl]carbamate is a solid with a crystalline form. It has a molecular weight of approximately 333.21 g/mol and a melting point of about 75-77°C. The compound is poorly soluble in water but soluble in organic solvents such as ethanol and chloroform. It is moderately reactive, showing partial N-dealkylation under basic conditions.

How is 2-Methyl-2-propanyl [1-(4-chlorophenyl)cyclobutyl]carbamate (CAS: 1032349-96-4) typically synthesized?

2-Methyl-2-propanyl [1-(4-chlorophenyl)cyclobutyl]carbamate is typically synthesized via a multistep reaction involving the formation of a carbamate from an amino alcohol and chlorophenyl cyclobutane. The reaction usually involves the use of a base like triethylamine and is carried out under an inert atmosphere. The overall yield is around 70-80%.

What industries use 2-Methyl-2-propanyl [1-(4-chlorophenyl)cyclobutyl]carbamate (CAS: 1032349-96-4)?

2-Methyl-2-propanyl [1-(4-chlorophenyl)cyclobutyl]carbamate (CAS: 1032349-96-4) is used in pharmaceuticals for its potential as an intermediate in drug synthesis. It is also utilized in the synthesis of various organic compounds and materials for sensor applications due to its reactive functional groups.

What precautions should be taken when handling 2-Methyl-2-propanyl [1-(4-chlorophenyl)cyclobutyl]carbamate (CAS: 1032349-96-4)?

When handling 2-Methyl-2-propanyl [1-(4-chlorophenyl)cyclobutyl]carbamate (CAS: 1032349-96-4), it is essential to use personal protective equipment (PPE) such as gloves, goggles, and a lab coat. It should be stored in a cool, dry place away from moisture and heat sources. Spills should be cleaned up immediately with appropriate absorbent materials, and proper disposal methods should be followed. Always refer to the Safety Data Sheet (SDS) for detailed handling and safety information.

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