1-Propionyl-4-piperidinecarboxylic acid | CAS No. 117705-17-6

1-Propionyl-4-piperidinecarboxylic acid

Basic Information

CAS Number

117705-17-6

Molecular Formula

C9H15NO3

Molecular Weight

185.22 g/mol

AD

Basic Physical Properties

CCC(=O)N1CCC(CC1)C(=O)O

InChI

InChI=1S/C9H15NO3/c1-2-8(11)10-5-3-7(4-6-10)9(12)13/h7H,2-6H2,1H3,(H,12,13)

InChIKey

XLUKLCQSTIHHLD-UHFFFAOYSA-N

LogP

0.7196000000000002

Topological Polar Surface Area

57.61 Ų

Hydrogen Bond Donor/Acceptor

1 / 4

Complexity

207

Safety Information

View Safety Information

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

  • 1-Propionylpiperidine-4-carboxylic acid
  • 1-propanoylpiperidine-4-carboxylic acid
  • 1-Propionyl-4-piperidinecarboxylic acid
  • NCGC00327040-01
  • 1-PROPIONYL-4-PIPERIDINECARBOXYLIC ACID
  • AKOS000129817
  • HMS1546D03
  • 117705-17-6
  • 4-Piperidinecarboxylic acid, 1-(1-oxopropyl)-
  • EU-0051881
  • DTXSID10350649
  • SR-01000520428
  • SR-01000520428-1
  • SB41708
  • SCHEMBL4259604
  • XLUKLCQSTIHHLD-UHFFFAOYSA-N
  • MFCD01414449
  • STK696190
  • Oprea1_842182
  • CS-0205155
  • TimTec1_004293
  • ALBB-012978
  • LS-04057
  • AB01322313-02

MDL Number

MFCD01414449

Customs Code

2933399090

FAQ

What are the physical and chemical properties of 1-Propionyl-4-piperidinecarboxylic acid (CAS: 117705-17-6)?

1-Propionyl-4-piperidinecarboxylic acid is a solid compound with a crystalline form. Its molecular weight is approximately 198.28 g/mol. It has low solubility in water but good solubility in organic solvents. Chemically, it is moderately reactive, particularly in esterification reactions. It has a pKa of around 4.5, indicating some acidity.

How is 1-Propionyl-4-piperidinecarboxylic acid (CAS: 117705-17-6) typically synthesized?

1-Propionyl-4-piperidinecarboxylic acid is typically synthesized through the condensation of propionyl chloride with 4-piperidinecarboxylic acid. The reaction is usually conducted under anhydrous conditions using a Lewis acid catalyst like aluminum chloride to improve selectivity and yield. The product is then purified by recrystallization or chromatography.

What industries use 1-Propionyl-4-piperidinecarboxylic acid (CAS: 117705-17-6)?

1-Propionyl-4-piperidinecarboxylic acid is used in various industries, including pharmaceuticals for drug synthesis, polymer chemistry for additive production, and sensors for detecting organic compounds. It is also utilized in the synthesis of semiconductors and as a building block in organic synthesis.

What precautions should be taken when handling 1-Propionyl-4-piperidinecarboxylic acid (CAS: 117705-17-6)?

When handling 1-Propionyl-4-piperidinecarboxylic acid, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Handle the material in a well-ventilated area or a fume hood. Spills should be cleaned up immediately with appropriate absorbent materials. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal instructions.

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