Methyl 6-bromoimidazo[1,2-a]pyridine-2-carboxylate(CAS: 354548-08-6)

Methyl 6-bromoimidazo[1,2-a]pyridine-2-carboxylate (CAS: 354548-08-6) is a crystalline solid with a molecular weight of approximately 281.03 g/mol. It has a high solubility in polar organic solvents such as DMSO and moderate solubility in water. The compound is moderately reactive and can undergo substitution reactions. It is stable under normal laboratory conditions but should be stored away from strong bases and reducing agents.

Methyl 6-bromoimidazo[1,2-a]pyridine-2-carboxylate is typically synthesized through an aromatic substitution reaction. The synthesis involves bromination of methyl imidazo[1,2-a]pyridine-2-carboxylate under an appropriate catalytic system, with a yield of up to 85%. Common solvents include DMF, and the reaction is monitored by TLC or GC methods.

Methyl 6-bromoimidazo[1,2-a]pyridine-2-carboxylate (CAS: 354548-08-6) is used in the pharmaceutical industry for the development of potential drug candidates. It is also utilized in the sensor industry due to its reactivity and stability properties. Additionally, it may have applications in the synthesis of functional polymers and as a precursor in semiconductor manufacturing.

When handling Methyl 6-bromoimidazo[1,2-a]pyridine-2-carboxylate (CAS: 354548-08-6), it is essential to wear appropriate personal protective equipment (PPE) including gloves, safety goggles, and a lab coat. The compound should be handled in a well-ventilated fume hood to avoid inhalation of fumes. Spills should be cleaned up with absorbent materials and disposed of according to local regulations. Always consult the Safety Data Sheet (SDS) for detailed handling and disposal procedures.