![2-Methyl-2-propanyl [1-(4-chlorophenyl)cyclobutyl]carbamate structure](https://static.chemtradehub.com/structs/103/1032349-96-4-11ab.webp "2-Methyl-2-propanyl [1-(4-chlorophenyl)cyclobutyl]carbamate structure")
2-Methyl-2-propanyl [1-(4-chlorophenyl)cyclobutyl]carbamate
CAS Number:
1032349-96-4
Molecular Formula:
C15H20ClNO2
5-{[Dimethyl(2-methyl-2-propanyl)silyl]oxy}-2-fluorobenzaldehyde | CAS No. 113984-67-1
5-{[Dimethyl(2-methyl-2-propanyl)silyl]oxy}-2-fluorobenzaldehyde
Basic Information
CAS Number
113984-67-1
Molecular Formula
C13H19FO2Si
Molecular Weight
254.38 g/mol
AD
Chemical Classification
Basic Physical Properties
Synonyms & References
English
- 5-(tert-butyl-dimethyl-silanyloxy)-2-fluoro-benzaldehyde
- Benzaldehyde, 5-[[(1,1-diMethylethyl)diMethylsilyl]oxy]-2-fluoro-
- 5-[(tert-butyldiMethylsilyl)oxy]-2- fluorobenzaldehyde
- 5-(tert-Butyldimethylsilyloxy)-2-fluorobenzaldehyde
MDL Number
MFCD17676576
FAQ
What are the physical and chemical properties of 5-{[Dimethyl(2-methyl-2-propanyl)silyl]oxy}-2-fluorobenzaldehyde (CAS: 113984-67-1)?
5-{[Dimethyl(2-methyl-2-propanyl)silyl]oxy}-2-fluorobenzaldehyde is a crystalline solid with a molecular weight of approximately 346.44 g/mol. It is slightly soluble in common organic solvents like ethanol and acetone. Chemically, it is known for its reactivity towards nucleophiles and its ability to participate in electrophilic aromatic substitution reactions. It has good stability under neutral to slightly acidic conditions, but it is sensitive to strong bases and oxidizing agents.
How is 5-{[Dimethyl(2-methyl-2-propanyl)silyl]oxy}-2-fluorobenzaldehyde (CAS: 113984-67-1) typically synthesized?
5-{[Dimethyl(2-methyl-2-propanyl)silyl]oxy}-2-fluorobenzaldehyde is typically synthesized through a silylation reaction of 2-fluorobenzaldehyde with dimethyl(2-methyl-2-propanyl)silyl chloride in the presence of a base such as imidazole. The reaction is carried out under anhydrous conditions to avoid hydrolysis. The yield is generally high, and the product shows good selectivity towards the desired silyl ether functionality.
What industries use 5-{[Dimethyl(2-methyl-2-proanyl)silyl]oxy}-2-fluorobenzaldehyde (CAS: 113984-67-1)?
5-{[Dimethyl(2-methyl-2-proanyl)silyl]oxy}-2-fluorobenzaldehyde is used in the pharmaceutical industry for the synthesis of certain drug molecules due to its functional groups, which can be further modified to introduce various pharmacophores. It also finds applications in the polymer industry for the development of functional polymers and in the semiconductor industry for the production of organic electronic materials.
What precautions should be taken when handling 5-{[Dimethyl(2-methyl-2-proanyl)silyl]oxy}-2-fluorobenzaldehyde (CAS: 113984-67-1)?
When handling 5-{[Dimethyl(2-methyl-2-proanyl)silyl]oxy}-2-fluorobenzaldehyde, it is important to wear appropriate personal protective equipment (PPE), including gloves, safety goggles, and a lab coat. The work should be carried out in a well-ventilated fume hood to minimize exposure to vapors. Spills should be cleaned up using appropriate absorbent materials, and the area should be thoroughly flushed with water. Always refer to the Material Safety Data Sheet (MSDS) for detailed safety information and emergency procedures.
Related Compounds
![4-Hydrazino-5-phenylthieno[2,3-d]pyrimidine structure](https://static.chemtradehub.com/structs/113/113246-86-9-b802.webp "4-Hydrazino-5-phenylthieno[2,3-d]pyrimidine structure")
![5-{[Dimethyl(2-methyl-2-propanyl)silyl]oxy}-2-fluorobenzaldehyde structure](https://static.chemtradehub.com/structs/113/113984-67-1-936e.webp "5-{[Dimethyl(2-methyl-2-propanyl)silyl]oxy}-2-fluorobenzaldehyde structure")
5-{[Dimethyl(2-methyl-2-propanyl)silyl]oxy}-2-fluorobenzaldehyde
CAS Number:
113984-67-1
Molecular Formula:
C13H19FO2Si
![Ethyl 1H-pyrazolo[3,4-B]pyridine-5-carboxylate structure](https://static.chemtradehub.com/structs/125/1256824-48-2-82de.webp "Ethyl 1H-pyrazolo[3,4-B]pyridine-5-carboxylate structure")
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