5-Bromo-2-methoxybenzylzinc chloride | CAS No. 352530-35-9
5-Bromo-2-methoxybenzylzinc chloride
Basic Information
CAS Number
352530-35-9
Molecular Formula
C8H8BrClOZn
Molecular Weight
300.9 g/mol
AD
Chemical Classification
Basic Physical Properties
Safety Information
View Safety InformationHazard Statement
H225
Highly Flammable liquid and vapor
Flammable liquids
Flammable liquids
H302
Harmful if swallowed
Acute toxicity, oral
Acute toxicity, oral
H314
Causes severe skin burns and eye damage
Skin corrosion/irritation
Skin corrosion/irritation
H335
May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation
H351
Suspected of causing cancer
Carcinogenicity
Carcinogenicity
Synonyms & References
English
- 5-bromo-2-methoxybenzylzinc chloride
- 4-bromo-2-methanidyl-1-methoxybenzene,chlorozinc(1+)
- 5-Bromo-2-methoxybenzylzinc chloride 0.5 M in Tetrahydrofuran
- 5-Bromo-2-methoxybenzylzinc chloride solution
- 5-Bromo-2-methoxybenzylzinc chloride, 0.5M in tetrahydrofuran
- MFCD02260144
- AKOS016017909
- 352530-35-9
- 5-BROMO-2-METHOXYBENZYLZINC CHLORIDE
MDL Number
MFCD02260144
Customs Code
2931900090
FAQ
What are the physical and chemical properties of 5-Bromo-2-methoxybenzylzinc chloride (CAS: 352530-35-9)?
5-Bromo-2-methoxybenzylzinc chloride is a crystalline compound with a molecular weight of approximately 338.3 g/mol. It is slightly soluble in water and more soluble in organic solvents. The compound is highly reactive, particularly towards elimination reactions. It has a melting point of around 58-60°C.
How is 5-Bromo-2-methoxybenzylzinc chloride (CAS: 352530-35-9) typically synthesized?
5-Bromo-2-methoxybenzylzinc chloride is typically synthesized by reacting 2-methoxybenzylzinc chloride with bromine in the presence of a base like sodium hydroxide. The reaction is carried out under mild conditions to ensure high selectivity and yield. This method provides a reliable route to the compound with good reproducibility.
What industries use 5-Bromo-2-methoxybenzylzinc chloride (CAS: 352530-35-9)?
5-Bromo-2-methoxybenzylzinc chloride is used in the pharmaceutical industry for the synthesis of various organic compounds, particularly in drug discovery and development. It is also employed in polymer science for the modification of polymers, and in semiconductor manufacturing for the production of certain organic semiconductors.
What precautions should be taken when handling 5-Bromo-2-methoxybenzylzinc chloride (CAS: 352530-35-9)?
When handling 5-Bromo-2-methoxybenzylzinc chloride, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or in a fume hood due to its reactivity and potential for off-gassing. In case of a spill, immediately clean up with appropriate absorbent materials and dispose of in a hazardous waste container. Always refer to the Safety Data Sheet (SDS) for detailed safety information.
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
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