5-Bromo-2-methoxybenzylzinc chloride(CAS: 352530-35-9)

5-Bromo-2-methoxybenzylzinc chloride is a crystalline compound with a molecular weight of approximately 338.3 g/mol. It is slightly soluble in water and more soluble in organic solvents. The compound is highly reactive, particularly towards elimination reactions. It has a melting point of around 58-60°C.

5-Bromo-2-methoxybenzylzinc chloride is typically synthesized by reacting 2-methoxybenzylzinc chloride with bromine in the presence of a base like sodium hydroxide. The reaction is carried out under mild conditions to ensure high selectivity and yield. This method provides a reliable route to the compound with good reproducibility.

5-Bromo-2-methoxybenzylzinc chloride is used in the pharmaceutical industry for the synthesis of various organic compounds, particularly in drug discovery and development. It is also employed in polymer science for the modification of polymers, and in semiconductor manufacturing for the production of certain organic semiconductors.

When handling 5-Bromo-2-methoxybenzylzinc chloride, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or in a fume hood due to its reactivity and potential for off-gassing. In case of a spill, immediately clean up with appropriate absorbent materials and dispose of in a hazardous waste container. Always refer to the Safety Data Sheet (SDS) for detailed safety information.