2-Bromo-3,4-difluoronitrobenzene

Basic Information

View in Editor

CAS Number

350699-92-2

Molecular Formula

C6H2BrF2NO2

Molecular Weight

237.99 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Boiling Point

227 ºC

Flash Point

91 ºC

SMILES

View in Editor

C1=CC(=C(C(=C1[N+](=O)[O-])Br)F)F

InChI

InChI=1S/C6H2BrF2NO2/c7-5-4(10(11)12)2-1-3(8)6(5)9/h1-2H

InChIKey

OANBJAYTIQWYDQ-UHFFFAOYSA-N

LogP

3.15870

Complexity

187

Safety Information

View Safety Information

Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

SY023241
SCHEMBL632916
FT-0658165
UNII-V85K7N7JGS
2-Bromo-3,4-difluoro-1-nitrobenzene #
J-508198
BENZENE, 2-BROMO-3,4-DIFLUORO-1-NITRO-
MP 1032 [WHO-DD]
AKOS005594035
AM62519
350699-92-2
2-Bromo-3,4-difluoro-1-nitrobenzene
2-Bromo-3,4-difluoro nitrobenzene
MFCD01820590
V85K7N7JGS
3-bromo-1,2-difluoro-4-nitrobenzene
2-Bromo-3,4-difluoronitrobenzene
CS-W002826
GS-3728
Benzene, 3-bromo-1,2-difluoro-4-nitro-
2-Bromo-3, 4-difluoro-nitrobenzene
DTXSID90341631
2-Bromo-3,4-Difluoronitrobenzene
2-brom-3,4-difluor-1-nitrobenzol
OANBJAYTIQWYDQ-UHFFFAOYSA-N
STK675783
CM12070
AS04960
VZ23909
LF10556
AS05639

MDL Number

MFCD01820590

Customs Code

2904909090

FAQ

What are the physical and chemical properties of 2-Bromo-3,4-difluoronitrobenzene (CAS: 350699-92-2)?

2-Bromo-3,4-difluoronitrobenzene (CAS: 350699-92-2) is a solid with a crystalline form. Its molecular weight is approximately 260.02 g/mol. It has low water solubility, with a solubility of about 0.1 g/L at 20°C. The compound is known for its stability under normal conditions but shows moderate reactivity in the presence of strong reducing or oxidizing agents. It is soluble in common organic solvents such as dichloromethane and acetonitrile. This compound is used in the preparation of pharmaceuticals, dyes, and other specialty chemicals.

How is 2-Bromo-3,4-difluoronitrobenzene (CAS: 350699-92-2) typically synthesized?

2-Bromo-3,4-difluoronitrobenzene (CAS: 350699-92-2) is typically synthesized through the electrophilic substitution of nitrobenzene with bromine and fluorine using silica gel as a catalyst at elevated temperatures. This process ensures high selectivity and good yield. The reaction involves the sequential introduction of bromine and fluorine atoms to the aromatic ring, followed by nitration to introduce the nitro group.

What industries use 2-Bromo-3,4-difluoronitrobenzene (CAS: 350699-92-2)?

2-Bromo-3,4-difluoronitrobenzene (CAS: 350699-92-2) is primarily used in the pharmaceutical and dye industries. It serves as a precursor in the synthesis of various drugs and pigments. Additionally, it finds applications in the production of sensors and semiconductors due to its unique electronic properties.

What precautions should be taken when handling 2-Bromo-3,4-difluoronitrobenzene (CAS: 350699-92-2)?

When handling 2-Bromo-3,4-difluoronitrobenzene (CAS: 350699-92-2), it is essential to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. Use a fume hood to minimize exposure to vapors. Store the compound in a cool, dry place away from heat and direct sunlight. In the event of a spill, immediately clean it up with appropriate absorbent materials and dispose of waste according to local regulations. Always consult the Safety Data Sheet (SDS) for detailed handling and disposal information.