2-Bromo-3,4-difluoronitrobenzene(CAS: 350699-92-2)

2-Bromo-3,4-difluoronitrobenzene (CAS: 350699-92-2) is a solid with a crystalline form. Its molecular weight is approximately 260.02 g/mol. It has low water solubility, with a solubility of about 0.1 g/L at 20°C. The compound is known for its stability under normal conditions but shows moderate reactivity in the presence of strong reducing or oxidizing agents. It is soluble in common organic solvents such as dichloromethane and acetonitrile. This compound is used in the preparation of pharmaceuticals, dyes, and other specialty chemicals.

2-Bromo-3,4-difluoronitrobenzene (CAS: 350699-92-2) is typically synthesized through the electrophilic substitution of nitrobenzene with bromine and fluorine using silica gel as a catalyst at elevated temperatures. This process ensures high selectivity and good yield. The reaction involves the sequential introduction of bromine and fluorine atoms to the aromatic ring, followed by nitration to introduce the nitro group.

2-Bromo-3,4-difluoronitrobenzene (CAS: 350699-92-2) is primarily used in the pharmaceutical and dye industries. It serves as a precursor in the synthesis of various drugs and pigments. Additionally, it finds applications in the production of sensors and semiconductors due to its unique electronic properties.

When handling 2-Bromo-3,4-difluoronitrobenzene (CAS: 350699-92-2), it is essential to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. Use a fume hood to minimize exposure to vapors. Store the compound in a cool, dry place away from heat and direct sunlight. In the event of a spill, immediately clean it up with appropriate absorbent materials and dispose of waste according to local regulations. Always consult the Safety Data Sheet (SDS) for detailed handling and disposal information.