How is 2-Bromo-3,4-difluoronitrobenzene (CAS: 350699-92-2) typically synthesized?

2-Bromo-3,4-difluoronitrobenzene (CAS: 350699-92-2) is typically synthesized through the electrophilic substitution of nitrobenzene with bromine and fluorine using silica gel as a catalyst at elevated temperatures. This process ensures high selectivity and good yield. The reaction involves the sequential introduction of bromine and fluorine atoms to the aromatic ring, followed by nitration to introduce the nitro group.