Disodium 2'-deoxy-5'-O-phosphonatoadenosine | CAS No. 2922-74-9
Disodium 2'-deoxy-5'-O-phosphonatoadenosine
Basic Information
CAS Number
2922-74-9
Molecular Formula
C10H12N5Na2O6P
Molecular Weight
375.19 g/mol
AD
Chemical Classification
Basic Physical Properties
Solubility
H2O: 50 mg/mL, clear, colorless
Synonyms & References
English
- disodium;[(2R,3S,5R)-5-(6-aminopurin-9-yl)-3-hydroxyoxolan-2-yl]methyl phosphate
- 2922-74-9
- AKOS015895716
- SCHEMBL543337
- 2'-deoxyadenosine-5'-monophosphate disodium salt
- 2'-Deoxyadenosine 5'-monophosphate disodium salt hydrate
- D82248
- dAMP hydrate
- Sodium ((2R,3S,5R)-5-(6-amino-9H-purin-9-yl)-3-hydroxytetrahydrofuran-2-yl)methyl phosphate
- 2'-deoxyadenosine 5'-monophosphate disodium salt
- C10H12N5Na2O6P
- Damp,(S)
- MFCD00065990
- 2'-Deoxyadenosine 5'-monophosphate disodium salt, >=97.0% (HPLC)
- dAMP pound not2Na
- 2'-Deoxyadenosine 5'-monophosphate sodium salt, Sigma Grade, >=96% (HPLC)
- Sodium((2R,3S,5R)-5-(6-amino-9H-purin-9-yl)-3-hydroxytetrahydrofuran-2-yl)methylphosphate
- 151151-31-4
- 5'-Adenylic acid,2'-deoxy-,disodium salt,hydrate(9ci)
- AC-32417
- 2'-Deoxyadenosine 5'-monophosphate, disodium salt
- disodium [(2R,3S,5R)-5-(6-amino-9H-purin-9-yl)-3-hydroxyoxolan-2-yl]methyl phosphate
- 5'-Adenylic acid, 2'-deoxy-, sodium salt (1:2)
- 2'-Deoxyadenosine 5'-monophpsphosphate disodium salt
- dAMP.2Na
- 2'-Deoxyadenosine-5'-monophosphate disodium salt
- disodium 2'-deoxyadenosine 5'-monophosphate
- Adenosine,2'-deoxy-, 5'-(dihydrogen phosphate), disodium salt (8CI)
- Adenosine,2'-deoxy-, 5'-phosphate, disodium salt (7CI)
- Deoxyadenosine 5'-monophosphatedisodium salt
- 2'-deoxyadenosine-5'-monophosphate
MDL Number
MFCD00065990
FAQ
What are the physical and chemical properties of Disodium 2'-deoxy-5'-O-phosphonatoadenosine (CAS: 2922-74-9)?
Disodium 2'-deoxy-5'-O-phosphonatoadenosine (CAS: 2922-74-9) is a crystalline compound with a molecular weight of approximately 467.16 g/mol. It has a solubility of about 0.1 mg/mL in water. This compound is generally stable under normal conditions but can be susceptible to hydrolysis under basic or acidic conditions. It is reactive towards nucleophilic substitution at the phosphonate group.
How is Disodium 2'-deoxy-5'-O-phosphonatoadenosine (CAS: 2922-74-9) typically synthesized?
Disodium 2'-deoxy-5'-O-phosphonatoadenosine (CAS: 2922-74-9) is typically synthesized via the phosphoramidite route, where 2'-deoxy-5'-O-phosphonatoadenosine is reacted with sodium hydroxide in an aqueous solution. This method ensures high selectivity and yield, with the use of sodium hydroxide as a catalyst. The reaction is performed under mild conditions and under an inert atmosphere to prevent decomposition.
What industries use Disodium 2'-deoxy-5'-O-phosphonatoadenosine (CAS: 2922-74-9)?
Disodium 2'-deoxy-5'-O-phosphonatoadenosine (CAS: 2922-74-9) is primarily used in the pharmaceutical industry for the synthesis of nucleoside analogs. It is also utilized in the polymer industry for the development of nucleic acid-based polymers. Additionally, it finds applications in the development of biosensors and as a building block for semiconductor materials due to its unique chemical properties.
What precautions should be taken when handling Disodium 2'-deoxy-5'-O-phosphonatoadenosine (CAS: 2922-74-9)?
When handling Disodium 2'-deoxy-5'-O-phosphonatoadenosine (CAS: 2922-74-9), it is essential to use appropriate personal protective equipment (PPE) such as gloves, lab coat, and safety goggles. The substance should be handled in a fume hood to minimize inhalation risks. Spills should be cleaned up using appropriate absorbent materials and disposed of according to local regulations. Always consult the Safety Data Sheet (SDS) for detailed handling and emergency procedures.
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
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