(3S)-3-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}-4-methylpentanoic acid | CAS No. 266318-79-0
(3S)-3-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}-4-methylpentanoic acid
Basic Information
CAS Number
266318-79-0
Molecular Formula
C21H23NO4
Molecular Weight
353.42 g/mol
AD
Basic Physical Properties
Boiling Point
563.9±33.0℃ at 760 mmHg
Solubility
Insuluble (6.4E-3 g/L) (25 ºC),
Synonyms & References
English
- (S)-3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-4-methylpentanoic acid
- Fmoc-D-beta-homovaline
- Fmoc-D-β-HomoVal-OH
- N-Fmoc-α-isopropyl-β-alanine
- Pentanoic acid,3-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-4-methyl-, (3S)-
- Fmoc-L-beta-homovaline
- Fmoc-D-β-Homo-Val
- FMOC-D--LEU-OH
- (3S)-3-({(9H-fluoren-9-yl)methoxycarbonyl}amino)-4-methylpentanoic acid
MDL Number
MFCD03095625
FAQ
What are the physical and chemical properties of (3S)-3-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}-4-methylpentanoic acid (CAS: 266318-79-0)?
The compound is an amide with a molecular weight of approximately 416.43 g/mol. It has a crystalline form and is insoluble in water but soluble in organic solvents. The compound is relatively stable under normal conditions but can react with strong bases or acids. It is not flammable and has a low reactivity under standard laboratory conditions.
How is (3S)-3-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}-4-methylpentanoic acid (CAS: 266318-79-0) typically synthesized?
This compound is typically synthesized through multistep organic synthesis, involving the coupling of fluorenylmethanol with an amino acid derivative. The process usually requires the use of coupling reagents such as HATU or EDC, and a base like DIPEA. The yield is generally around 70-80%, and the reaction is performed under anhydrous conditions to avoid side reactions.
What industries use (3S)-3-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}-4-methylpentanoic acid (CAS: 266318-79-0)?
This compound is primarily used in the pharmaceutical industry for the synthesis of drug candidates. It also has applications in the polymer industry for developing new materials with specific properties. Additionally, it may be used in sensors and semiconductors for its unique chemical structure, although its commercial use in these areas is less common.
What precautions should be taken when handling (3S)-3-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}-4-methylpentanoic acid (CAS: 266318-79-0)?
When handling this compound, it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to minimize inhalation risks. Spills should be cleaned up carefully using appropriate absorbents, and the area should be decontaminated. Refer to the Material Safety Data Sheet (MSDS) for specific safety guidelines and emergency procedures.
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
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