4,5-Dichloro-2-thiophenesulfonamide

Basic Information

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CAS Number

256353-34-1

Molecular Formula

C4H3Cl2NO2S2

Molecular Weight

232.11 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Agricultural Chemicals Pesticides Herbicides

Water Treatment Chemicals Coagulants and Flocculants Inorganic Coagulants

Basic Physical Properties

Melting Point

152-155°C

Boiling Point

405.3°Cat760mmHg

Density

1.761

Flash Point

198.9°C

Refractive Index

1.631

SMILES

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C1=C(SC(=C1Cl)Cl)S(=O)(=O)N

InChI

InChI=1S/C4H3Cl2NO2S2/c5-2-1-3(10-4(2)6)11(7,8)9/h1H,(H2,7,8,9)

InChIKey

JKBNSTFOQDGQLS-UHFFFAOYSA-N

LogP

1.7023000000000004

Topological Polar Surface Area

60.160000000000004 Å²

Hydrogen Bond Donor/Acceptor

2 / 3

Complexity

237

Safety Information

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GHS Hazard Pictograms

H302

H315

H319

H335

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

4,5-dichloro-thiophene-2-sulfonic acid amide
A851035
FT-0644137
AKOS015897373
EN300-1725792
4,5-Dichlorothiophene-2-sulfonamide
CS-W010361
SB17891
A5152
SCHEMBL1137322
MFCD00177161
J-506941
2,3-Dichlorothiophene-5-sulfonamide
FS-3940
256353-34-1
JKBNSTFOQDGQLS-UHFFFAOYSA-N
DTXSID80395522
AC-4586
P18414
4,5-Dichloro-2-thiophenesulfonamide
2,3,5-TRI-O-BENZYL-BETA-L-ARABINOFURANOSE
2,3-Dichlorthiophen-5-sulfamid
4,5-Dichlor-thiophen-2-sulfonsaeure-amid
4,5-dichlorothiophene-2-sulfonamide

MDL Number

MFCD00177161

Customs Code

2935009090

FAQ

What are the physical and chemical properties of 4,5-Dichloro-2-thiophenesulfonamide (CAS: 256353-34-1)?

4,5-Dichloro-2-thiophenesulfonamide (CAS: 256353-34-1) is a crystalline solid with a molecular weight of approximately 247.03 g/mol. It has a low solubility in water but is more soluble in organic solvents like dichloromethane and acetonitrile. The compound is relatively stable under normal conditions but can react with reducing agents. It is important to handle it under proper laboratory conditions to avoid unwanted reactions.

How is 4,5-Dichloro-2-thiophenesulfonamide (CAS: 256353-34-1) typically synthesized?

4,5-Dichloro-2-thiophenesulfonamide (CAS: 256353-34-1) is commonly synthesized via the sulfonation of 2-chlorothiophene followed by chlorination. The process involves using sulfur trioxide or chlorosulfonic acid as the sulfonating agent and chlorine gas for chlorination. The reaction is typically carried out in the presence of a suitable catalyst to achieve high selectivity and yield.

What industries use 4,5-Dichloro-2-thiophenesulfonamide (CAS: 256353-34-1)?

4,5-Dichloro-2-thiophenesulfonamide (CAS: 256353-34-1) is primarily used in the pharmaceutical industry for the synthesis of various organic compounds. It is also utilized in the polymer industry for modifying the properties of plastics and resins. Additionally, it can be used in the development of sensors and as a component in semiconductor manufacturing processes.

What precautions should be taken when handling 4,5-Dichloro-2-thiophenesulfonamide (CAS: 256353-34-1)?

When handling 4,5-Dichloro-2-thiophenesulfonamide (CAS: 256353-34-1), it is crucial to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or with a fume hood to minimize inhalation risk. Spills should be cleaned up using appropriate absorbents, and the material safety data sheet (MSDS) should be consulted for detailed emergency procedures and disposal methods.