4-(1-Piperazinyl)-1H-indole dihydrochloride | CAS No. 255714-24-0
4-(1-Piperazinyl)-1H-indole dihydrochloride
Basic Information
CAS Number
255714-24-0
Molecular Formula
C12H17Cl2N3
Molecular Weight
274.2 g/mol
AD
Basic Physical Properties
Melting Point
300-303
Safety Information
View Safety InformationHazard Statement
Synonyms & References
English
- 4-(Piperazin-1-yl)-1H-indole--hydrogen chloride (1/2)
- 4-piperazin-1-yl-1H-indole;dihydrochloride
- 4-(piperazin-1-yl)-1H-indole dihydrochloride
- SCHEMBL6730585
- FT-0644135
- 1H-Indole-4-(1-piperazinyl) dihydrochloride
- 4-(Piperazinyl)-1H-indole dihydrochloride
- DTXSID80655118
- AKOS016016047
- 4-(1-piperazinyl)-1h-indole dihydrochloride
- 4-(piperazin-1-yl)-1H-indoledihydrochloride
- MFCD00829148
- AKOS005254359
- F17540
- SR-01000946760-1
- PD020366
- 4-piperazin-1-yl-1h-indole dihydrochloride
- 4-(1-Piperazinyl)-1H-indole dihydrochloride, AldrichCPR
- 4-(1-piperazinyl)-1H-Indole, dihydrochloride
- TS-03535
- 255714-24-0
- SR-01000946760
- EN300-299898
- 1H-Indole,4-(1-piperazinyl)-, hydrochloride (1:2)
- 4-(1-piperazinyl)-1H-Indole (hydrochloride)
- 4-Piperazin-1-yl-1H-indole dihydrochloride
- 4-Piperazinoindole dihydrochloride
- 1H-Indole-4-(1-piperazinyl)dihydrochloride
- 4-(1-Piperazinyl)-1H-indole dihydrochloride
MDL Number
MFCD00829148
Customs Code
2933990090
FAQ
What are the physical and chemical properties of 4-(1-Piperazinyl)-1H-indole dihydrochloride (CAS: 255714-24-0)?
4-(1-Piperazinyl)-1H-indole dihydrochloride is a crystalline white powder with a molecular weight of approximately 355.75 g/mol. It has a low solubility in water but is more soluble in organic solvents like ethanol and dichloromethane. It is slightly basic due to the presence of the chloride salt. This compound is thermally stable but may react with strong bases or oxidizing agents.
How is 4-(1-Piperazinyl)-1H-indole dihydrochloride (CAS: 255714-24-0) typically synthesized?
4-(1-Piperazinyl)-1H-indole dihydrochloride is typically synthesized by the reaction of 4-hydroxyindole with piperazine in the presence of an acid catalyst such as hydrochloric acid. The reaction is carried out at room temperature, and the product is isolated by recrystallization from an appropriate solvent. The yield is moderate, and the purity is high.
What industries use 4-(1-Piperazinyl)-1H-indole dihydrochloride (CAS: 255714-24-0)?
4-(1-Piperazinyl)-1H-indole dihydrochloride is primarily used in the pharmaceutical industry as an intermediate in the synthesis of certain drugs. It is also used in the chemical industry for the development of new materials and in the sensing technology sector for the fabrication of gas sensors.
What precautions should be taken when handling 4-(1-Piperazinyl)-1H-indole dihydrochloride (CAS: 255714-24-0)?
When handling 4-(1-Piperazinyl)-1H-indole dihydrochloride, it is important to use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be performed in a well-ventilated area or a fume hood to avoid inhalation. Spills should be cleaned up carefully using appropriate chemicals and procedures. Always refer to the Safety Data Sheet (SDS) for detailed safety information.
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
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