Compound Q&A
How is 4-(1-Piperazinyl)-1H-indole dihydrochloride (CAS: 255714-24-0) typically synthesized?
Answer
4-(1-Piperazinyl)-1H-indole dihydrochloride is typically synthesized by the reaction of 4-hydroxyindole with piperazine in the presence of an acid catalyst such as hydrochloric acid. The reaction is carried out at room temperature, and the product is isolated by recrystallization from an appropriate solvent. The yield is moderate, and the purity is high.
About
CAS No
255714-24-0
English Name
4-(1-Piperazinyl)-1H-indole dihydrochloride
Molecular Formula
C12H17Cl2N3
Molecular Weight
274.2 g/mol
SMILES
C1CN(CCN1)C2=CC=CC3=C2C=CN3.Cl.Cl
InChIKey
FHRAUNYCUBSDMF-UHFFFAOYSA-N
Last Updated: 2026-03-08 04:51
