2-Amino-6-bromobenzoic acid

Basic Information

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CAS Number

20776-48-1

Molecular Formula

C7H6BrNO2

Molecular Weight

216.03 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Fine Chemicals Dyes and Pigments Organic Dyes

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Physical State

Solid

Melting Point

134-135 °C

Boiling Point

348.9℃ at 760 mmHg

Density

1.793

Flash Point

164.8℃

Refractive Index

1.672

SMILES

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C1=CC(=C(C(=C1)Br)C(=O)O)N

InChI

InChI=1S/C7H6BrNO2/c8-4-2-1-3-5(9)6(4)7(10)11/h1-3H,9H2,(H,10,11)

InChIKey

BNQPROAXWQCNKO-UHFFFAOYSA-N

LogP

1.7295

Topological Polar Surface Area

63.32000000000001 Å²

Hydrogen Bond Donor/Acceptor

3 / 3

Complexity

163

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class IRRITANT Class IRRITANT

Sensitiveness

Light Sensitive

Synonyms & References

English

Z228589666
6-Bromoanthranilic acid
2-amino-6-bromo-benzoic Acid
SY005767
SCHEMBL9092
EN300-65905
2-Amino-6-bromobenzoic acid, AldrichCPR
W-201821
20776-48-1
DTXSID80441750
2-(TERT-BUTYLSULFONYL)ACETAMIDEOXIME
PS-3610
A4516
AKOS005257127
MFCD03618455
FT-0600113
CS-W003094
AM20060219
Benzoic acid, 2-amino-6-bromo-
3-Bromo-2-carboxyaniline
2-Amino-6-bromobenzoic acid
BNQPROAXWQCNKO-UHFFFAOYSA-N
2-Amino-6-brom-benzoesaeure
2-amino-6-bromo-benzoic acid
6-Brom-anthranilsaeure
6-Bromoanthranilic Acid
KSC201S8R
Anthranilicacid, 6-bromo- (6CI,8CI)
2-amino-6-bromobenzoic acid

MDL Number

MFCD03618455

Customs Code

2922499990

FAQ

What are the physical and chemical properties of 2-Amino-6-bromobenzoic acid (CAS: 20776-48-1)?

2-Amino-6-bromobenzoic acid is a crystalline solid with a molecular weight of approximately 267.02 g/mol. It has a low solubility in water (0.1 g/100 mL at 20°C) and exhibits typical reactivity of carboxylic acids and amines. It is moderately acidic and can undergo substitution reactions in the presence of amines and nucleophiles.

How is 2-Amino-6-bromobenzoic acid (CAS: 20776-48-1) typically synthesized?

2-Amino-6-bromobenzoic acid can be synthesized via bromination of 2-aminobenzoic acid followed by purification. Commonly, bromine in acetone is used as the brominating agent. The reaction is selective and yields a high percentage of the target compound. Additionally, catalytic hydrogenation of 2-bromo-6-nitrobenzoic acid can also produce this compound.

What industries use 2-Amino-6-bromobenzoic acid (CAS: 20776-48-1)?

2-Amino-6-bromobenzoic acid finds applications in pharmaceuticals, particularly in the development of organic dyes and pigments for colorimetric sensors. It is also used in the synthesis of certain azo dyes and as an intermediate in the production of various polymers and semiconductor materials.

What precautions should be taken when handling 2-Amino-6-bromobenzoic acid (CAS: 20776-48-1)?

When handling 2-Amino-6-bromobenzoic acid, it is essential to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or fume hood to minimize inhalation risks. Spills should be handled with caution, using appropriate cleanup procedures, and the substance should be stored in a cool, dry place away from direct sunlight. Always refer to the Safety Data Sheet (SDS) for specific handling instructions and emergency procedures.