2-Bromo-3-nitropyridine

Basic Information

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CAS Number

19755-53-4

Molecular Formula

C5H3BrN2O2

Molecular Weight

202.99 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Agricultural Chemicals Pesticides Herbicides

Water Treatment Chemicals Coagulants and Flocculants Inorganic Coagulants

Basic Physical Properties

Melting Point

122.0 to 125.0 deg-C

Boiling Point

244℃ at 760 mmHg

Flash Point

101.4℃

Refractive Index

1.6200 (estimate)

SMILES

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C1=CC(=C(N=C1)Br)[N+](=O)[O-]

InChI

InChI=1S/C5H3BrN2O2/c6-5-4(8(9)10)2-1-3-7-5/h1-3H

InChIKey

ZCCUFLITCDHRMG-UHFFFAOYSA-N

LogP

2.27550

Complexity

136

Safety Information

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GHS Hazard Pictograms

H315

H319

H335

Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

B4193
BCP21921
PB12717
A4327
Pyridine, 2-bromonitro-
RB1072
2-Bromo-3-nitro-pyridine
2-Bromo-3-nitropyridine, 98%
19755-53-4
2-Bromo-3-nitropyridine
InChI=1/C5H3BrN2O2/c6-5-4(8(9)10)2-1-3-7-5/h1-3
FT-0637893
AC-7417
Pyridine, 2-bromo-3-nitro-
SCHEMBL653567
Q-101227
DTXSID20339263
SY006161
AM20061810
AKOS005175089
CS-W015483
EN300-103885
FG-0482
2-Bromo-3-nitropyridine #
BB 0261228
MFCD00955613
DS-0844
2-Brom-3-nitro-pyridin
2-bromo-3-nitro-pyridine
2-bromonitropyridine
3-Nitro-2-bromopyridine

MDL Number

MFCD00955613

Customs Code

2933399090

FAQ

What are the physical and chemical properties of 2-Bromo-3-nitropyridine (CAS: 19755-53-4)?

2-Bromo-3-nitropyridine is a crystalline solid with a molecular weight of approximately 228.03 g/mol. It has a melting point of around 115-118°C and is slightly soluble in most common organic solvents. It shows significant reactivity towards nucleophiles and can undergo substitution reactions at the bromine and nitro groups.

How is 2-Bromo-3-nitropyridine (CAS: 19755-53-4) typically synthesized?

2-Bromo-3-nitropyridine is typically synthesized through the nitration of 2-bromopyridine followed by selective reduction of the nitro group to an amine. This process often uses concentrated nitric acid and sulfuric acid as reagents, and requires careful monitoring of reaction conditions to achieve high selectivity and yield.

What industries use 2-Bromo-3-nitropyridine (CAS: 19755-53-4)?

2-Bromo-3-nitropyridine is used in the pharmaceutical industry for the synthesis of certain medicinal compounds. It also finds applications in the development of sensors and semiconductors due to its electronic properties.

What precautions should be taken when handling 2-Bromo-3-nitropyridine (CAS: 19755-53-4)?

Proper personal protective equipment (PPE) such as gloves, goggles, and a lab coat is essential when handling 2-Bromo-3-nitropyridine. It should be stored in a cool, dry place away from direct sunlight and sources of heat. In the event of a spill, it should be cleaned up immediately using appropriate absorbent materials, and the area should be well-ventilated. Safety data sheets (SDS) should always be consulted for detailed handling and disposal instructions.