2-Bromo-3-nitropyridine(CAS: 19755-53-4)

2-Bromo-3-nitropyridine is a crystalline solid with a molecular weight of approximately 228.03 g/mol. It has a melting point of around 115-118°C and is slightly soluble in most common organic solvents. It shows significant reactivity towards nucleophiles and can undergo substitution reactions at the bromine and nitro groups.

2-Bromo-3-nitropyridine is typically synthesized through the nitration of 2-bromopyridine followed by selective reduction of the nitro group to an amine. This process often uses concentrated nitric acid and sulfuric acid as reagents, and requires careful monitoring of reaction conditions to achieve high selectivity and yield.

2-Bromo-3-nitropyridine is used in the pharmaceutical industry for the synthesis of certain medicinal compounds. It also finds applications in the development of sensors and semiconductors due to its electronic properties.

Proper personal protective equipment (PPE) such as gloves, goggles, and a lab coat is essential when handling 2-Bromo-3-nitropyridine. It should be stored in a cool, dry place away from direct sunlight and sources of heat. In the event of a spill, it should be cleaned up immediately using appropriate absorbent materials, and the area should be well-ventilated. Safety data sheets (SDS) should always be consulted for detailed handling and disposal instructions.