Acetylcorynoline

Basic Information

View in Editor

CAS Number

18797-80-3

Molecular Formula

C23H23NO6

Molecular Weight

409.43 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Esters

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Physical State

Cryst.

Solubility

Methanol,Dichloromethane,Chloroform,DMSO

SMILES

View in Editor

CC(=O)OC1Cc2cc3OCOc3cc2C2C1(C)c1ccc3c(c1CN2C)OCO3

InChI

InChI=1S/C23H23NO6/c1-12(25)30-20-7-13-6-18-19(28-10-27-18)8-14(13)22-23(20,2)16-4-5-17-21(29-11-26-17)15(16)9-24(22)3/h4-6,8,20,22H,7,9-11H2,1-3H3

InChIKey

PUHCFWFODBLSAP-UHFFFAOYSA-N

LogP

3.076200000000002

Topological Polar Surface Area

66.46000000000001 Å²

Hydrogen Bond Donor/Acceptor

0 / 7

Complexity

703

Safety Information

View Safety Information

Storage Conditions

2-8℃

Synonyms & References

English

[1,3]Benzodioxolo[5,6-c]-1,3-dioxolo[4,5-i]phenanthridin-6-ol,5b,6,7,12b,13,14-hexahydro-5b,13-dimethyl-, 6-acetate, (5bR,6S,12bR)-
[1,3]Benzodioxolo[5,6-c]-1,3-dioxolo[4,5-i]phenanthridin-6-ol,5b,6,7,12b,13,14-hexahydro-5b,13...
acetyl corynoline
(+)-Corynolin-acetat
(+)-Corynolin-O-acetat
(+)-O-acetyl-corynoline
(5bR)-6t-acetoxy-5b,13-dimethyl-(5br,12bc)-5b,6,7,12b,13,14-hexahydro-[1,3]dioxolo[4,5-i][1,3]dioxolo[4',5':4,5]benzo[1,2-c]phenanthridine
corynoline acetate
N1513
O-acetyl-13-methyl-chelidonine
(5bR,6S,12bR)-5b,6,7,12b,13,14-Hexahydro-5b,13-dimethyl-[1,3]benzodioxolo[5,6-c]-1,3-dioxolo[4,5-i]phenanthridin-6-ol 6-acetate
O-Acetylcorynoline
ACETYLCORYNOLINE(P)
Acetylcorynoline
Corynoline, acetate (ester)
(+)-Corynoline acetate
(+)-Corynoline acetate,Corynoline acetate

MDL Number

MFCD28385837

FAQ

What are the physical and chemical properties of Acetylcorynoline (CAS: 18797-80-3)?

Acetylcorynoline (CAS: 18797-80-3) is a crystalline compound with a molecular weight of approximately 254.31 g/mol. It has a solubility of about 0.2 mg/mL in water and is slightly soluble in ethanol. Chemically, it is relatively stable but can react with strong acids or bases. It is an amphoteric compound with potential for both acidic and basic behavior.

How is Acetylcorynoline (CAS: 18797-80-3) typically synthesized?

Acetylcorynoline (CAS: 18797-80-3) is commonly synthesized through a route involving the acetylation of corynoline, a natural product. The synthesis typically requires the use of acetic anhydride as the acylating agent, with a base like sodium hydride. The reaction is typically carried out in a polar aprotic solvent such as dimethylformamide (DMF) under anhydrous conditions. High selectivity and good yield are achieved under these conditions.

What industries use Acetylcorynoline (CAS: 18797-80-3)?

Acetylcorynoline (CAS: 18797-80-3) is utilized in various industries, primarily in pharmaceuticals due to its biological activity. It is also explored in the field of natural products chemistry for its potential as a lead compound. Additionally, it may have applications in the development of new materials and sensors, though its use in these areas is less common and more research-based.

What precautions should be taken when handling Acetylcorynoline (CAS: 18797-80-3)?

When handling Acetylcorynoline (CAS: 18797-80-3), it is essential to wear appropriate personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat. It should be stored in a cool, dry place away from direct sunlight. In case of a spill, it should be cleaned up using appropriate absorbent materials and disposed of according to local regulations. Always consult the Safety Data Sheet (SDS) for detailed handling and disposal instructions.