Acetylcorynoline(CAS: 18797-80-3)

Acetylcorynoline (CAS: 18797-80-3) is a crystalline compound with a molecular weight of approximately 254.31 g/mol. It has a solubility of about 0.2 mg/mL in water and is slightly soluble in ethanol. Chemically, it is relatively stable but can react with strong acids or bases. It is an amphoteric compound with potential for both acidic and basic behavior.

Acetylcorynoline (CAS: 18797-80-3) is commonly synthesized through a route involving the acetylation of corynoline, a natural product. The synthesis typically requires the use of acetic anhydride as the acylating agent, with a base like sodium hydride. The reaction is typically carried out in a polar aprotic solvent such as dimethylformamide (DMF) under anhydrous conditions. High selectivity and good yield are achieved under these conditions.

Acetylcorynoline (CAS: 18797-80-3) is utilized in various industries, primarily in pharmaceuticals due to its biological activity. It is also explored in the field of natural products chemistry for its potential as a lead compound. Additionally, it may have applications in the development of new materials and sensors, though its use in these areas is less common and more research-based.

When handling Acetylcorynoline (CAS: 18797-80-3), it is essential to wear appropriate personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat. It should be stored in a cool, dry place away from direct sunlight. In case of a spill, it should be cleaned up using appropriate absorbent materials and disposed of according to local regulations. Always consult the Safety Data Sheet (SDS) for detailed handling and disposal instructions.