Tert-butyl 4-(1-hydroxyethyl)piperidine-1-carboxylate

Basic Information

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CAS Number

183170-69-6

Molecular Formula

C12H23NO3

Molecular Weight

229.32 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

SMILES

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CC(C1CCN(CC1)C(=O)OC(C)(C)C)O

InChI

InChI=1S/C12H23NO3/c1-9(14)10-5-7-13(8-6-10)11(15)16-12(2,3)4/h9-10,14H,5-8H2,1-4H3

InChIKey

SQOMPUDOUGDJPH-UHFFFAOYSA-N

LogP

2.0143

Topological Polar Surface Area

49.769999999999996 Å²

Hydrogen Bond Donor/Acceptor

1 / 4

Complexity

239

Synonyms & References

English

4-(1-HYDROXY-ETHYL)-PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER
tert-butyl 4-(1-hydroxyethyl)piperidine-1-carboxylate
1,1-Dimethylethyl 4-(1-hydroxyethyl)-1-piperidinecarboxylate
1-tert-Butoxycarbonyl-4-(1-hydroxyethyl)piperidine
1-Boc-4-(1-hydroxyethyl)-piperidine
SY037706
SCHEMBL387237
AM100421
1-tert-Butoxycarbonyl-4-(1-hydroxyethyl)piperidine; 4-(1-Hydroxyethyl)piperidine-1-carboxylic acid tert-butyl ester
SY344339
MFCD15474944
TERT-BUTYL 4-(1-HYDROXYETHYL)PIPERIDINE-1-CARBOXYLATE
SB23153
1-(1-Boc-4-piperidyl)ethanol
DTXSID90621268
EN300-3572171
DA-09003
183170-69-6
AKOS022931227
TERT-BUTYL4-(1-HYDROXYETHYL)PIPERIDINE-1-CARBOXYLATE
SQOMPUDOUGDJPH-UHFFFAOYSA-N
CS-0011606
N-tert-butoxycarbonyl-4-(1-hydroxyethyl)piperidine
1-Piperidinecarboxylic acid, 4-(1-hydroxyethyl)-, 1,1-dimethylethyl ester
MFCD22666104
(S)-1-Boc-4-(1-hydroxyethyl)piperidine
N-t-Butoxycarbonyl-4-(1-hydroxyethyl)piperidine
(+/-)-1,1-dimethylethyl 4-(1-hydroxyethyl)-1-piperidinecarboxylate
1-Boc-4-(1-Hydroxyethyl)piperidine
AS-42642
SY035992

MDL Number

MFCD15474944

FAQ

What are the physical and chemical properties of Tert-butyl 4-(1-hydroxyethyl)piperidine-1-carboxylate (CAS: 183170-69-6)?

Tert-butyl 4-(1-hydroxyethyl)piperidine-1-carboxylate has a crystalline form with a molecular weight of approximately 255.4 g/mol. It is slightly soluble in water and more soluble in organic solvents. The compound is moderately reactive, particularly in the presence of acid or base conditions, and can undergo hydrolysis and esterification reactions.

How is Tert-butyl 4-(1-hydroxyethyl)piperidine-1-carboxylate (CAS: 183170-69-6) typically synthesized?

Tert-butyl 4-(1-hydroxyethyl)piperidine-1-carboxylate is typically synthesized through the reaction of tert-butyl piperidine-1-carboxylate with 1-hydroxyethyl chloride. Commonly, this process involves a multi-step procedure involving protection, substitution, and deprotection, using mild organic solvents and appropriate catalysts to achieve high yield and selectivity.

What industries use Tert-butyl 4-(1-hydroxyethyl)piperidine-1-carboxylate (CAS: 183170-69-6)?

Tert-butyl 4-(1-hydroxyethyl)piperidine-1-carboxylate is used in the pharmaceutical industry for the synthesis of drug intermediates. It is also utilized in the polymer industry for the modification of polymers, and in the semiconductor industry for the production of functional materials. Additionally, it has applications in sensor technology and as a chemical reagent.

What precautions should be taken when handling Tert-butyl 4-(1-hydroxyethyl)piperidine-1-carboxylate (CAS: 183170-69-6)?

When handling Tert-butyl 4-(1-hydroxyethyl)piperidine-1-carboxylate, it is essential to use appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. Handle the compound in a well-ventilated area or fume hood to minimize exposure to vapors. Spills should be handled according to the material safety data sheet (MSDS/SDS) guidelines. Always consult the SDS for detailed safety information and follow all safety protocols.