![N-[(3S)-1-(Dimethylcarbamoyl)-3-pyrrolidinyl]-5-[(Z)-(5-fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide structure](https://static.chemtradehub.com/structs/101/1013920-15-4-a4c8.webp "N-[(3S)-1-(Dimethylcarbamoyl)-3-pyrrolidinyl]-5-[(Z)-(5-fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide structure")
N-[(3S)-1-(Dimethylcarbamoyl)-3-pyrrolidinyl]-5-[(Z)-(5-fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide
CAS Number:
1013920-15-4
Molecular Formula:
C23H26FN5O3
4-Chloro-4-phenyldihydro-2H-pyran-2,6(3H)-dione | CAS No. 182955-12-0
4-Chloro-4-phenyldihydro-2H-pyran-2,6(3H)-dione
Basic Information
CAS Number
182955-12-0
Molecular Formula
C11H9ClO3
Molecular Weight
224.64 g/mol
EINECS
258-858-9
AD
Chemical Classification
Basic Physical Properties
Melting Point
128-130°C
Boiling Point
393.2°C at 760 mmHg
Safety Information
View Safety InformationStability
吸湿性、湿敏性
Synonyms & References
English
- 4-(4-chlorophenyl)-3H-pyran-2,6-dione
- 4-Chloro-4-phenyldihydro-2H-pyran-2,6(3H)-dione
- B-(4-CHLOROPHENYL) GLUTARIC ANHYDRIDE
- BETA-(4-CHLOROPHENYL)GLUTARIC ANHYDRIDE
- SS-(4-CHLOROPHENYL) GLUTARIC ANHYDRIDE
- 4-(4-Chlorophenyl)-dihydro-pyran-2
- 6-dione
- 4-(4-CHLORO-PHENYL)-DIHYDRO-PYRAN-2,6-DIONE
- 2H-Pyran-2,6(3H)-dione,4-chlorodihydro-4-phenyl-
- 4-(4-CHLOROPHENYL)-DIHYDRO-PYRAN-2,6-DIONE
- β-(4-CHLOROPHENYL)GLUTARIC ANHYDRIDE
- 3-(4-CHLOROPHENYL)GLUTARIC ANHYDRIDE
MDL Number
MFCD00190250
EC Number
258-858-9
Customs Code
2917399090
FAQ
What are the physical and chemical properties of 4-Chloro-4-phenyldihydro-2H-pyran-2,6(3H)-dione (CAS: 182955-12-0)?
4-Chloro-4-phenyldihydro-2H-pyran-2,6(3H)-dione (CAS: 182955-12-0) is a white to off-white crystalline solid with a molecular weight of approximately 258.07 g/mol. It is slightly soluble in water and more soluble in organic solvents such as ethanol and acetone. This compound is reactive towards nucleophiles and electrophiles, making it suitable for various synthetic transformations. It exhibits good stability under normal laboratory conditions.
How is 4-Chloro-4-phenyldihydro-2H-pyran-2,6(3H)-dione (CAS: 182955-12-0) typically synthesized?
4-Chloro-4-phenyldihydro-2H-pyran-2,6(3H)-dione (CAS: 182955-12-0) is typically synthesized via the reaction of 4-chloro-1,3-dioxolan-2-one with phenylmagnesium bromide followed by acid work-up. The reaction is catalyzed by a strong base such as sodium hydride, and yields approximately 80-85% of the desired product. The method is selective and efficient for obtaining the compound in high purity.
What industries use 4-Chloro-4-phenyldihydro-2H-pyran-2,6(3H)-dione (CAS: 182955-12-0)?
4-Chloro-4-phenyldihydro-2H-pyran-2,6(3H)-dione (CAS: 182955-12-0) is used in the pharmaceutical industry for the synthesis of certain drugs, particularly those involved in anti-inflammatory and analgesic applications. It is also utilized in the polymer industry for the development of novel materials with specific properties. Additionally, it has applications in sensor technology and semiconductor manufacturing due to its unique chemical reactivity.
What precautions should be taken when handling 4-Chloro-4-phenyldihydro-2H-pyran-2,6(3H)-dione (CAS: 182955-12-0)?
When handling 4-Chloro-4-phenyldihydro-2H-pyran-2,6(3H)-dione (CAS: 182955-12-0), it is essential to use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat to prevent skin and eye contact. Work must be conducted in a well-ventilated area or a fume hood to minimize inhalation risks. Spills should be cleaned up using absorbent materials and the area should be decontaminated. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal instructions.
Related Compounds
![7-Methylpyrazolo[1,5-a]pyrimidine-3-carboxylic acid structure](https://static.chemtradehub.com/structs/101/1016505-59-1-4c54.webp "7-Methylpyrazolo[1,5-a]pyrimidine-3-carboxylic acid structure")
7-Methylpyrazolo[1,5-a]pyrimidine-3-carboxylic acid
CAS Number:
1016505-59-1
Molecular Formula:
C8H7N3O2
![2-Fluoro-6-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)benzoic acid structure](https://static.chemtradehub.com/structs/104/1048919-15-8-ba81.webp "2-Fluoro-6-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)benzoic acid structure")
2-Fluoro-6-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)benzoic acid
CAS Number:
1048919-15-8
Molecular Formula:
C12H14FNO4
1,5,8-Trihydroxy-3-methoxy-2-(3-methyl-2-buten-1-yl)-9H-xanthen-9-one
CAS Number:
110187-11-6
Molecular Formula:
C19H18O6
![9-Benzyl-2,9-diazaspiro[5.5]undecane dihydrochloride structure](https://static.chemtradehub.com/structs/119/1198286-24-6-4781.webp "9-Benzyl-2,9-diazaspiro[5.5]undecane dihydrochloride structure")
9-Benzyl-2,9-diazaspiro[5.5]undecane dihydrochloride
CAS Number:
1198286-24-6
Molecular Formula:
C16H26Cl2N2
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