2-Methyl-2-propanyl 4-piperidinylcarbamate hydrochloride (1:1) | CAS No. 179110-74-8

2-Methyl-2-propanyl 4-piperidinylcarbamate hydrochloride (1:1)

Basic Information

CAS Number

179110-74-8

Molecular Formula

C10H21ClN2O2

Molecular Weight

236.74 g/mol

AD

Basic Physical Properties

CC(C)(C)OC(=O)NC1CCNCC1.Cl

InChI

InChI=1S/C10H20N2O2.ClH/c1-10(2,3)14-9(13)12-8-4-6-11-7-5-8;/h8,11H,4-7H2,1-3H3,(H,12,13);1H

InChIKey

VVLJVJSHANVSGD-UHFFFAOYSA-N

LogP

1.6848999999999996

Topological Polar Surface Area

50.36 Ų

Hydrogen Bond Donor/Acceptor

2 / 4

Complexity

193

Synonyms & References

English

  • Carbamic acid, N-4-piperidinyl-, 1,1-dimethylethyl ester, hydrochloride (1:1)
  • tert-Butyl piperidin-4-ylcarbamate hydrochloride
  • Piperidin-4-yl-carbamic acid tert-butyl ester hydrochloride
  • FT-0653067
  • SCHEMBL4158527
  • tert-Butyl 4-amino-1-piperidinecarboxylate hydrochloride
  • tert-Butyl piperidin-4-ylcarbamate HCl
  • Piperidin4-yl-carbamic acid tert-butyl ester hydrochloride
  • MFCD03093509
  • AKOS015897677
  • A812424
  • tert-butyl N-piperidin-4-ylcarbamate;hydrochloride
  • SB43306
  • 4-BOC-AMINOPIPERIDINE-HCl
  • DS-14039
  • 4-(boc-amino)piperidine hydrochloride
  • tert-Butylpiperidin-4-ylcarbamatehydrochloride
  • 4-boc-aminopiperidine hcl
  • VVLJVJSHANVSGD-UHFFFAOYSA-N
  • 179110-74-8
  • 4-tert-Butoxycarbonylaminopiperidine hydrochloride
  • (Boc-4-aMino)piperidine hydrochloride
  • 4-N-BOC-Aminopiperidine hcl
  • Carbamic acid,N-4-piperidinyl-, 1,1-dimethylethyl ester, hydrochloride (1:1)
  • 4-(Boc-amino)-piperidine hydrochloride
  • Piperidin-4-ylcarbamic acid tert-butyl ester hydrochloride
  • Piperidin-4-ylcarbamic acid tert-butyl ester monohydrochloride
  • tert-butyl 4-amino-1-piperidinecarboxylate hydrochloride
  • ST2419988
  • AX8209501
  • W3900

MDL Number

MFCD03093509

FAQ

What are the physical and chemical properties of 2-Methyl-2-propanyl 4-piperidinylcarbamate hydrochloride (CAS: 179110-74-8)?

2-Methyl-2-propanyl 4-piperidinylcarbamate hydrochloride (CAS: 179110-74-8) is a crystalline solid with a molecular weight of approximately 234.3 g/mol. It is slightly soluble in water and soluble in organic solvents such as ethanol and acetone. The compound exhibits moderate reactivity in acidic conditions and is stable in neutral to basic conditions. It has a pKa of about 3.5.

How is 2-Methyl-2-propanyl 4-piperidinylcarbamate hydrochloride (CAS: 179110-74-8) typically synthesized?

2-Methyl-2-propanyl 4-piperidinylcarbamate hydrochloride (CAS: 179110-74-8) is typically synthesized via the reaction of 2-methyl-2-propanol and 4-piperidone in the presence of a suitable base such as sodium hydroxide. The reaction is conducted in an aqueous medium, and hydrochloric acid is added post-reaction to form the hydrochloride salt. The product is then purified by recrystallization from an appropriate solvent.

What industries use 2-Methyl-2-propanyl 4-piperidinylcarbamate hydrochloride (CAS: 179110-74-8)?

2-Methyl-2-propanyl 4-piperidinylcarbamate hydrochloride (CAS: 179110-74-8) is primarily used in the pharmaceutical industry as an intermediate in the synthesis of various drugs. It may also find applications in the polymer industry as a stabilizer or plasticizer. Additionally, it could be used in biosensors and as a chiral auxiliary in asymmetric synthesis.

What precautions should be taken when handling 2-Methyl-2-propanyl 4-piperidinylcarbamate hydrochloride (CAS: 179110-74-8)?

Proper handling of 2-Methyl-2-propanyl 4-piperidinylcarbamate hydrochloride (CAS: 179110-74-8) requires the use of personal protective equipment (PPE) such as gloves, goggles, and a lab coat. It should be handled in a fume hood due to its potential for release of hydrogen chloride gas. Spills should be handled carefully, using suitable absorbents and following safety guidelines. Always refer to the Safety Data Sheet (SDS) for detailed information on handling and disposal.

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