2,2-Bis(trimethylsilyl)acetamide | CAS No. 17879-45-7

2,2-Bis(trimethylsilyl)acetamide

Basic Information

CAS Number

17879-45-7

Molecular Formula

C8H21NOSi2

Molecular Weight

203.43 g/mol

AD

Basic Physical Properties

C[Si](C)(C)C(C(=O)N)[Si](C)(C)C

InChI

InChI=1S/C8H21NOSi2/c1-11(2,3)8(7(9)10)12(4,5)6/h8H,1-6H3,(H2,9,10)

InChIKey

NDVMCQUOSYOQMZ-UHFFFAOYSA-N

LogP

2.0574999999999997

Topological Polar Surface Area

43.09 Ų

Hydrogen Bond Donor/Acceptor

2 / 2

Synonyms & References

English

  • BIS-TRIMETHYLSILYLACETAMIDE
  • nhsa
  • BSA-C
  • AC-BSA
  • ALBUMIN, PIG
  • albumenpowder
  • SERUM ALBUMIN
  • ACETYLATED BSA
  • BSA ACETYLATED
  • Bovine albumin
  • BSA, METHYLATED
  • 2,2-bis(trimethylsilyl)acetamide
  • 2,2-bis(trimethylsilyl)ethanamide
  • A800911
  • Acetamide, 2,2-bis(trimethylsilyl)-
  • AGN-PC-00EJUT
  • bis(trimethylsilyl)acetamide
  • bis(trimethyl-silyl)acetamide
  • bistrimethylsilyl acetamide
  • CTK0A6853
  • N,O-bis(trimethylsilyl)acetamide

Customs Code

3502900000

FAQ

What are the physical and chemical properties of 2,2-Bis(trimethylsilyl)acetamide (CAS: 17879-45-7)?

2,2-Bis(trimethylsilyl)acetamide (CAS: 17879-45-7) is a colorless, crystalline solid with a molecular weight of approximately 214.37 g/mol. It is highly soluble in organic solvents but poorly soluble in water. Chemically, it is a weak base and exhibits limited reactivity under normal conditions, making it suitable for a wide range of applications in organic chemistry.

How is 2,2-Bis(trimethylsilyl)acetamide (CAS: 17879-45-7) typically synthesized?

2,2-Bis(trimethylsilyl)acetamide is typically synthesized by the reaction of acetic anhydride with trimethylsilyl chloride in the presence of a base such as triethylamine. The reaction is carried out at room temperature, and the yield is usually around 90%. This method provides high selectivity and good purity of the product.

What industries use 2,2-Bis(trimethylsilyl)acetamide (CAS: 17879-45-7)?

2,2-Bis(trimethylsilyl)acetamide (CAS: 17879-45-7) is widely used in various industries. It is an essential reagent in the synthesis of pharmaceuticals and polymers. Additionally, it finds applications in the production of sensors and semiconductors, where its stabilizing properties are particularly valuable.

What precautions should be taken when handling 2,2-Bis(trimethylsilyl)acetamide (CAS: 17879-45-7)?

When handling 2,2-Bis(trimethylsilyl)acetamide (CAS: 17879-45-7), safety should be a top priority. Wear appropriate personal protective equipment (PPE), including gloves and safety goggles. Store the compound in a well-ventilated area and avoid contact with water or other inorganic acids. In case of a spill, clean up using appropriate absorbent materials and dispose of the waste according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed safety information.

Related Compounds

You might also like

Compound Q&A

What is 6-Methyl-7-oxabicyclo[4.1.0]heptan-2-one (CAS: 21889-89-4)?

6-Methyl-7-oxabicyclo[4.1.0]heptan-2-one is a cyclic ketone with a molecular for...

21889-89-46-Methyl-7-oxabicycl...
Compound Q&A

What is 4-[(6-Methyl-2-pyrazinyl)oxy]benzoic acid (CAS: 906353-00-2)?

4-[(6-Methyl-2-pyrazinyl)oxy]benzoic acid is a chemical compound with the CAS nu...

906353-00-24-[(6-Methyl-2-pyraz...
Compound Q&A

What is 2-(2-Pyridinyl)-1,3-propanediol (CAS: 49745-42-8)?

2-(2-Pyridinyl)-1,3-propanediol (CAS: 49745-42-8) is a colorless to slightly yel...

49745-42-82-(2-Pyridinyl)-1,3-...
Compound Q&A

What is 2-(6-Chloro-2-pyridinyl)-2-phenylacetonitrile (CAS: 24783-42-4)?

2-(6-Chloro-2-pyridinyl)-2-phenylacetonitrile is an organic compound with the CA...

24783-42-42-(6-Chloro-2-pyridi...
Compound Q&A

What is 2-Oxopropanamide (CAS: 631-66-3)?

2-Oxopropanamide, also known as 2-aminoacrylic acid, is a chemical compound with...

631-66-32-Oxopropanamide
Compound Q&A

What is 2-Methyl-2-propanyl 4-(5-bromo-6-methyl-2-pyridinyl)-1-piperazinecarboxylate (CAS: 1289040-88-5)?

2-Methyl-2-propanyl 4-(5-bromo-6-methyl-2-pyridinyl)-1-piperazinecarboxylate (CA...

1289040-88-52-Methyl-2-propanyl ...
Compound Q&A

What is NAMPT inhibitor-linker 1 (CAS: 2241019-57-6)?

NAMPT inhibitor-linker 1 (CAS: 2241019-57-6) is a chemical compound designed as ...

2241019-57-6NAMPT inhibitor-link...
Compound Q&A

What is (2-(2,2,2-Trifluoroacetyl)pyridin-4-yl)boronic acid (CAS: 1310404-58-0)?

It is a chemical compound with the structure (2-(2,2,2-Trifluoroacetyl)pyridin-4...

1310404-58-0(2-(2,2,2-Trifluoroa...
Compound Q&A

What is 1-(2-Chlorophenyl)-6-(3,3,3-trifluoro-2-methylpropyl)-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one (CAS: 794568-90-4)?

1-(2-Chlorophenyl)-6-(3,3,3-trifluoro-2-methylpropyl)-1,5-dihydro-4H-pyrazolo[3,...

794568-90-41-(2-Chlorophenyl)-6...
Compound Q&A

What is Vinyl(chloromethyl)dimethoxysilane (CAS: 1314981-48-0)?

Vinyl(chloromethyl)dimethoxysilane is an organosilicon compound with the molecul...

1314981-48-0Vinyl(chloromethyl)d...