N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N-[4-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)butyl]glycine | CAS No. 171856-09-0
N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N-[4-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)butyl]glycine
Basic Information
CAS Number
171856-09-0
Molecular Formula
C26H32N2O6
Molecular Weight
468.55 g/mol
AD
Basic Physical Properties
Safety Information
View Safety InformationGHS Hazard Pictograms
H410Hazard Statement
H410
Very toxic to aquatic life with long lasting effects
Hazardous to the aquatic environment, long-term hazard
Hazardous to the aquatic environment, long-term hazard
Synonyms & References
English
- J-010768
- CS-0201699
- 2-((((9H-Fluoren-9-yl)methoxy)carbonyl)(4-((tert-butoxycarbonyl)amino)butyl)amino)acetic acid
- Fmoc-N-(4-Boc-aminobutyl)glycine
- MNAXPVXIHALBEF-UHFFFAOYSA-N
- 2-((((9H-fluoren-9-yl)methoxy)carbonyl)(4-(tert-butoxycarbonylamino)butyl)amino)acetic acid
- Fmoc-{Boc-NH(CH2)4}Gly-OH
- 2-[9H-fluoren-9-ylmethoxycarbonyl-[4-[(2-methylpropan-2-yl)oxycarbonylamino]butyl]amino]acetic acid
- Fmoc-Abg(Boc)-OH
- FT-0701226
- AKOS015911531
- Fmoc-N-(4-Boc-aminobutyl)-Gly-OH
- [(4-tert-Butoxycarbonylamino-butyl)-(9H-fluoren-9-ylmethoxycarbonyl)-amino]-acetic acid
- SCHEMBL4599714
- N-(9-Fluorenylmethyloxycarbonyl)-N-[4-(t-butyloxycarbonylamino)butyl]-glycine
- N-[4-(Boc-amino)butyl]-N-Fmoc-glycine
- 2-[(4-{[(tert-butoxy)carbonyl]amino}butyl)({[(9H-fluoren-9-yl)methoxy]carbonyl})amino]acetic acid
- DTXSID70373278
- 171856-09-0
- N-(((9H-Fluoren-9-yl)methoxy)carbonyl)-N-(4-((tert-butoxycarbonyl)amino)butyl)glycine
- Glycine,N-[4-[[(1,1-dimethylethoxy)carbonyl]amino]butyl]-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-
- MFCD04112689
- E70683
- AS-81598
- HY-W141907
- Fmoc-N-(4-Boc-aminobutyl)-Gly-OH, >=98.0% (HPLC)
- Fmoc-abg(boc)-oh
- FMOC-N-(4-BOC-AMINOBUTYL)GLYCINE,
- AC1MBSYF
- CTK8F0790
- Fmoc-Nlys(Boc)-OH
MDL Number
MFCD04112689
Customs Code
29242990
FAQ
What are the physical and chemical properties of N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N-[4-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)butyl]glycine (CAS: 171856-09-0)?
This compound is a crystalline solid with a molecular weight of approximately 610.55 g/mol. It has limited water solubility and is highly reactive, particularly with bases. It is stable under normal conditions but should be protected from moisture. Reactivity is enhanced in basic conditions, making it suitable for peptide coupling reactions.
How is N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N-[4-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)butyl]glycine (CAS: 171856-09-0) typically synthesized?
The compound is synthesized through a multi-step process involving fluorenylmethyloxycarbonyl (Fmoc) protection, followed by amidation and acylation reactions. Commonly, the Fmoc group is introduced using Fluorenylmethoxycarbonyl chloride (Fmoc-Cl), and the product is purified by column chromatography. This process requires careful control of pH and temperature to ensure high yield and selectivity.
What industries use N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N-[4-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)butyl]glycine (CAS: 171856-09-0)?
This compound is primarily used in pharmaceuticals, where it serves as an intermediate in the synthesis of complex peptides and proteins. It is also utilized in polymer science for the modification of polymers and in semiconductor manufacturing for specific surface chemistry applications.
What precautions should be taken when handling N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N-[4-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)butyl]glycine (CAS: 171856-09-0)?
When handling this compound, it is essential to wear appropriate personal protective equipment (PPE), including gloves, goggles, and lab coat. Work should be conducted in a well-ventilated area or fume hood to avoid inhalation. Spills should be cleaned up carefully using appropriate safety measures, and the Material Safety Data Sheet (MSDS) should be consulted for detailed handling instructions.
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
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